Leukaemia Cutis: An Unusual Presentation of T-cell Acute Lymphoblastic Leukaemia in an Adult Patient
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 3
Abstract
: Leukaemia cutis is coetaneous manifestation of leukemia. Because of wide range of cutaneous manifestations, it is clinically difficult to make distinguish leukemia cutis from other skin lesions. Patients with leukaemia cutis commonly have concomitant systemic leukemia, but occasionally it has been observed that cutaneous preceds the involvement of bone marrow or peripheral blood. Thus, a skin biopsy can be the first indication of the leukemia in a subset of patients. Moreover, the immunophenotyping of routinely processed skin biopsy specimens is useful for the confirmation of the diagnosis of Leukemia Cutis. Cutaneous manifestation of hematologic malignancies in adult is uncommon. A 24 year old boy presented with multiple skin nodules on the limbs, face, trunk and abdomen. Histopathology and flow cytometry established the diagnosis of T cell acute lymphoblastic leukemia. This case is being presented for its rarity and clinical interest. Keywords: Acute lymphoblastic leukemia, T-cell, Skin nodules.
Authors and Affiliations
Lohit kumar Kalita, Chayanika Kalita, Mir Alam Siddique, Pabitra Kamar Gogoi, Umesh Ch. Sarma
Keywords
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