Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation: The presentation of a rare case

Journal Title: Cumhuriyet Medical Journal - Year 2018, Vol 40, Issue 1

Abstract

Characterized by brain stem and spinal cord involvement and elevated lactate level, leukoencephalopathy (LBSL) is a white matter disease that has been newly described on the basis of magnetic resonance imaging (MRI) signs. The clinical signs and symptoms indicate progressive pyramidal, cerebellar, and dorsal column dysfunction. Its laboratory findings are generally non-revealing. There are some typical MRI and magnetic resonance spectroscopy (MRS) signs. We present a 11-year-old boy patient with cerebellar, pyramidal and dorsal column dysfunctions and specific MRI and characteristic MRS findings. MRI and MRS findings were consistent with LBSL. LBSL is a rare leukoencephalopathy. The imaging features are very specific, and radiology has a key role to play in directing the diagnosis and management.

Authors and Affiliations

Mehmet H. Atalar, Abdurrahman Gölbaşı, Bülent Yıldız

Keywords

Related Articles

The relationship between I-131 uptake in postoperative residue thyroid tissue and absorbed doses calculated with MIRDOSE3 and pre-ablation thyroglobulin levels in patients with differential thyroid cancer: A retrospective comparison study

Objective: The aim of this study was to compare I-131 uptake in postoperative residue thyroid tissue and absorbed doses calculated with MIRDOSE3 and pre-ablation thyroglobulin levels in patients with differential thyroid...

The effects of ozone on the local and systemic interleukin 1β (IL-1β) and IL-10 levels experimental periodontitis model in rats

Objective: The purpose of this study was to analyze the morphometric and histopathologic changes associated with experimental periodontitis in rats in response to the administration of ozone. Method: Twenty-four rats wer...

Overutilization of proton pump inhibitors and H2 receptor antagonists in hospitalized medical patients

Objective: The aim of the study was to determine the frequency of the use of proton pump inhibitors (PPI) and histamine-2 receptor antagonists (H2RA), which are widely used drugs, in the medical wards. Method: We retrosp...

Domestic violence crimes between 2008-2011 in Turkey

Objective: The purpose of this study; by collecting official data from the Ministry of Justice, analysing trends in time and differences among cities and regions. Method: Criminal data was taken from the criminal courts...

Is there diagnostic and prognostic importance of serum anti-p53 antibody level in lung cancer?

Objective: Lung cancer is the leading cause of cancer-related deaths worldwide. Despite advancement in diagnostic tools and treatment options with technological developments, overall mortality rates in lung cancer patien...

Download PDF file
  • EP ID EP272137
  • DOI 10.7197/223.vi.407600
  • Views 100
  • Downloads 0

How To Cite

Mehmet H. Atalar, Abdurrahman Gölbaşı, Bülent Yıldız (2018). Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation: The presentation of a rare case. Cumhuriyet Medical Journal, 40(1), 797-800. https://europub.co.uk/articles/-A-272137