Level of indicators of immune reactivity in blood of rats under conditions of one-time intragastric administration of the mixture of nano-particles of metals (ag, fe, cu, mn dioxide)
Journal Title: Біоресурси і природокористування [Biological Resources and Nature Management] - Year 2017, Vol 9, Issue 5
Abstract
Metal nanoparticles (NPMe) in the form of colloidal dispersions - is one of the most bioavailable forms of Me in comparison with the traditionally used salts of corresponding metals. Blood as one of the biological fluids in the body corresponds to qualitative and quantitative changes in its composition to any exogenous and endogenous factors, that is a unique biomarker, and the study of clinical and biochemical parameters of blood is one of the informative methods that allows to establish the transition of the physiological state of the organism to the pathological. The aim of the research was to determine the level of indices of humoral and cellular immunity links in rat blood under conditions of one-time intragastric administration of a mixture of NPMe (Ag, Cu, Fe, Mn dioxide) in a dose range compared to a mixture of salts of corresponding metals.
Authors and Affiliations
M. Ye. Roman'ko
Keywords
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