Levels of Cortisol, Progesterone, Prolactin with Liver Enzymes and Lipid Profile in First Trimester Pregnant Iraqi Women
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Astudy was conducted to investigate the changes insome hormones, lipid profileand liver enzymes in the first trimester pregnant Iraqi women as compared with the apparently healthy control women. A total of 60 women included30 pregnant women at first trimester selected from women admitted to Gynecology Department at Medical City of Baghdad Teaching Hospital, all pregnant women aged between (20-35) yearsandcompared with30 apparently healthy women. The cortisol, progesterone,and prolactin hormones were measured using BiomerieuxMinividas Model: vidas12, while lipid profile,liver enzymes and some kidney function test (urea,creatinine) were evaluated by colorimetric method using a spectrophotometer.Results showedasignificantincreasing(P<0.01)in cortisol (30.52 ng/ml), progesterone(39.91 ng/ml), and prolactin (72.85 ng/ml) in pregnant women as compared to the corresponding means of 3.80, 0.83, and 22.20 ng/ml in the control group. TheLDL level (99.70 mg/dl) was significantly increased(P<0.01)in pregnant as compared with 71.62 mg/dl in the control ,while HDL was significantly (P<0.01) decreased in the pregnant. The level of the ALP, ALT, and AST was significantly lower (P<0.05) in pregnant than control. It was found a positive significant correlation between the three hormones and BMI,HDL whilethe correlations between theses hormones and each of LDL,ALK,ALT and AST were negative.The progesterone and prolactin showed asignificant correlation(P<0.05) with cholesterol.In conclusion: The serum cortisol, prolactin and progesteronewere significantly increased (P<0.05) during pregnancy in comparison with thenon-pregnant group, there was alsoa significant increasing(P<0.05) in cholesterol and LDL in pregnant women, kidneyfunction testsshowed non-significant difference, while liver enzymes were within normal range.
Authors and Affiliations
Prof. Ali Sh. Sultan, Noor AlhudaKh Ibrahim, Ban H. Hameedi3, Prof. Bushra F. Hasan 4
Keywords
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- EP ID EP390161
- DOI 10.9790/3008-1204055156
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