LEVOFLOXACIN ORAL CHALLENGE TEST
Journal Title: Journal of Medical Sciences - Year 2016, Vol 19, Issue 2
Abstract
Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. It has been defined by the British Society for Allergy and Clinical Immunology (BSACI) as 'an ADR with an established immunological mechanism' 1,2 . Diagnostic procedures in allergy diagnosis can be classified into the patient's history, in vivo skin testing, in vitro laboratory tests and provocation tests 3 . In situations in which there is a definite medical need for a particular agent, no suitable alternative agent exists, there are primarily two options for the patient with a drug allergy; a procedure to induce temporary drug tolerance can be performed to allow the patient to take the drug safely or a test dose or graded challenge can be administered to determine whether the patient is currently allergic to the particular drug .4
Authors and Affiliations
Taha Qureshi, Roohi Rasool, Qurteeba Qadri, Talib Khan, Zaffar Amin Shah
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