Lichen myxedematosus - diagnostic difficulties. A case report
Journal Title: Postępy Dermatologii i Alergologii - Year 2006, Vol 23, Issue 3
Abstract
Lichen myxedematosus (papular mucinosis) comprises the group of conditions associated with deposition of mucin in the skin. Because of considerable variability and complexity of its forms, this rare dermatosis may often cause diagnostic difficulties. New and updated classification of lichen myxedematosus by Rongioletti and Rebora [1] includes 3 variants of the disease: generalized (scleromyxedema), localized and atypical. Lichen myxedematosus is often recognized as a chronic benign condition, however, in its generalized form it may be associated with monoclonal gammopathy (mostly types IgG λ and κ) and its course may be unfavorable for the patient. In the case of lichen myxedematosus both choice and efficacy of the treatment depend significantly on disease variant and the majority of literature reports refer to the treatment with glucocorticosteroids, cytostatic agents, interferon α, plasmapheresis, photoferesis, radiation therapy and PUVA-therapy (including PUVA-bath).
Authors and Affiliations
Dorota Jenerowicz, Monika Bowszyc-Dmochowska, Agnieszka Ziembicka, Karolina Piotrowska, Anna Neneman
Keywords
Related Articles
- EP ID EP107417
- DOI -
- Views 75
- Downloads 0
Usefulness of chosen molecular techniques in analysis of mutation of NF1 gene in patients with neurofibromatosis type I
Neurofibromatosis is genetic disease with autosomal dominant inheritance. The most frequent form is neurofibromatosis type I (NFI). The onset of the disease is in early childhood or late. Clinical manifestations include...
Badanie stężenia E-selektyny w surowicy u chorych z chorobą
Chociaż objaw Raynauda jest pierwszą charakterystyczną manifestacją twardziny układowej (SSc), tylko u niewielkiej części chorych z tym objawem rozwija się choroba tkanki łącznej. Celem badania była ocena znaczenia E-se...
Management of venous leg ulcers - modern wound dressings
Venous leg ulcers arising from pathophysiological processes appearing in the course of chronic venous insufficiency can be classified also as the chronic wounds, which is due both to the character and the duration of the...
Lipomatosis benigna - Launois-Bensaude syndrome. Surgical treatment
Authors present the patient with Launois-Bensaude syndrome because of its rare occurence and good effects of multi-stage surgical therapy. Etiology of this pathological state is unknown. Many cases are connected with al...
Substance P, vasoactive intestinal peptide and nerve growth factor involvement in the pathogenesis of few dermatoses
Neuropeptides act as neuromodulators, neurotransmitters, neurotrophins and neurohormons and are involved in the transmission of signals between nerve cells and immune cells. They are produced mostly in afferent, unmyelin...