LINEAR ALKYL BENZENE SULPHONATE, A DETERGENT INDUCED TOXICITY ON THE GILL OF PUNTIUS TICTO FISH
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 10
Abstract
Detergents are common household products used for cleaning of domestic materials. The ‘after wash’ of the detergents are either drained into the aquatic environment such as ponds, lakes, rivers, streams, etc. or they find their way into the aquatic environment by natural sewage. Hence in the present study, the acute toxic and histopathological effects of a detergent, “Linear Alkyl Benzene Sulphonate” (LABS) on the gill of Puntius ticto (a teleost fish) were evaluated. For acute toxicity study, the fishes were exposed to LABS (Henko) in graded concentrations (20-28 mg/L, except 22 mg/L) for 24, 48, 72 and 96 hr duration. All 30 (100%) fishes were died in the Henko concentration of 28 mg/L at 24 hr, indicating that the acute toxicity of LABS is dose dependent. The LC50 of Henko was found to be 25.5 mg/L. For histopathological study, the fishes were exposed to 2 mg/L Henko for one month. The histopathological examination of Henko-treated fish gill revealed severe changes in the epithelial lining of gill arch, gill rakers and gill filaments, suggesting that the LABS may induce the abnormal cellular structure in gill.
Authors and Affiliations
Varsha Jain , K. D. Mishra , S. Madhuri , Govind Pandey
Keywords
Related Articles
- EP ID EP103293
- DOI -
- Views 106
- Downloads 0
A REVIEW ON FLOATING TYPE GASTRORETENTIVE DRUG DELIVERY SYSTEM
Oral controlled release delivery systems are programmed to deliver the drug in predictable time frame that will increase the efficacy and minimize the adverse effects and increase the bioavailability of drugs. Oral route...
ANATOMICAL STANDARDIZATION OF CAPPARIS ZEYLANICA L.
The genus Capparis L. is shrubs or rarely tree, erect, scandent or sprawling; shoots generally armed with stipular spines and belonging to the family Capparadaceae. The Capparis zeylanica L. is anodyne, sedative, stomach...
ASSESSMENT OF ANXIOLYTIC ACTIVITY OF AQUEOUS EXTRACT OF MANGIFERA INDICA L. LEAVES IN RODENTS EXPOSED TO CHRONIC UNPREDICTABLE MILD STRESS
The purpose of this study was to characterize the anxiolytic activity of an Aqueous extract prepared from the leaves of Mangifera indica L (AEMI) using an elevated plus maze (EPM) model in rat and staircase model in mice...
A NEW MODEL FOR INFLAMMATORY BOWEL DISEASE IN RATS
Here we report the Lipopolysaccharide (LPS) induced rat model of Inflammatory Bowel Disease (IBD). Toll Like Receptor-4 (TLR-4) are reported to be upregulated in IBD and LPS is recognized by TLRs of the innate immune sys...
ENHANCING SOLUBILITY AND DISSOLUTION OF CELECOXIB BY SPRAY DRYING TECHNIQUE
Celecoxib, a selective COX-2 inhibitor, exhibits poor water solubility, dissolution and flow properties. Thus, the aim of the present study was to improve the solubility and dissolution rate of celecoxib by preparing cry...