Lipid profile of patients with diabetes mellitus: a cross sectional study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Background: Dyslipidemia is one of the common disorders which is seen in most of the diabetic patients, which causes cardio vascular disorders. Objective: To detect the lipid abnormality in diabetic patients. Methods: The study was carried out in Medicine Department, at a tertiary care hospital, Visakhapatnam from March 2017 to June 2017. The lipid profiles and the blood sugar values of 60 diabetic patients and 60 healthy subjects were studied after taking informed consent. Their serum samples were assessed for fasting blood glucose (FBG), post prandial blood glucose(PPBS), total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL) and high density lipoprotein cholesterol (HDL) by using standard biochemical methods. The data was collected by predesigned, pretested proforma and analyzed using SPSS 17.0 (Trial version). Results: Maximum number of patients (36.6%) were from age group of 40-49 years. Mean age in DM group was 42.13 ± 9.29 years. Among males with diabetes 43.3% were in the 50-59yrs age group. Among females with diabetes 46% were in the 30-39yrs age group. Among Diabetic patients only 26.6% had fasting blood glucose less than 140mg/dl and 23.3% showed more than 200 mg/dl level of Post Prandial Blood Sugar (PPBS). All the subjects with diabetes mellitus showed high serum cholesterol level (>240mg/dl). Among Diabetic patients showed normal (<150 mg/dl) serum triglyceride level, whereas all the control group subjects showed normal level. Serum LDL level was high (>160 mg/dl ) in 98.3% of Diabetic patients. In diabetic patients group 41.6% of them showed low (<40 mg/dl) serum HDL value whereas in the control group all the participants had normal serum HDL level(>40mg/dl). In DM patients, the mean values of S. Cholesterol and S. LDL were high whereas S. triglyceride and S. HDL level were in normal limit in both the sexes. Males have shown slightly higher mean level of S. cholesterol, S. triglyceride, S. LDL and S. HDL level as compared to females. Conclusions: The frequencies of the high cholesterol, high TG and high LDL levels were higher in the diabetic group, thus indicating that diabetic patients were more prone for dyslipidemia, which could cause cardiovascular disorders.
Authors and Affiliations
P. Eswara Rao, J. S. Surya Prabha . Kona
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