Lipoprotein A in Diabetic Retinopathy
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Background: Type-2 diabetes mellitus is an increasingly common metabolic abnormality associated with microvascular and macrovascular complications, one of which is diabetic retinopathy which is the most common cause of visual loss in adults in the developed countries. Atherogenic lipoproteins such as total cholesterol, LDL cholesterol, oxidized low density lipoprotein, and triglycerides are associated with progression of retinopathy. Aim: To evaluate the relationship between lipoprotein A, Lp(a) and retinopathy in patients with type 2 diabetes mellitus. Material and Methods: 100 diabetic patients were enrolled in the study. Presence of retinopathy were evaluated. Serum lipid profile including Lp(a) level was assessed. Results: High Lp(a) levels have been observed in patients with diabetic retinopathy as compared to those without retinopathy. Conclusion: Lp(a) levels are increased in a significant percentage of patients with retinopathy compared to diabetic patients without retinopathy. The impact of Lp(a) levels on diabetic retinopathy needs to be further investigated.
Authors and Affiliations
Tamphasana Wairokpam, K. Sorojini Devi
Keywords
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- EP ID EP452690
- DOI 10.9790/0853-1801193034.
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