Livedoid Vasculopathy: A Case Report and Review of Literature
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Livedoid Vasculopathy (LV) is a chronic vascular disorder due to vascular coagulopathies that is characterized by recurrent painful ulcers that usually involves the lower legs especially the ankles. Here in we report a case of LV in a 50-year- old obese female presented with 6-month-history of persistent painful skin ulcers. She is a known to have hypertension on treatment. She also has history of deep vein thrombosis (DVT) 5 years ago (not on any treatment now). Skin examination showed multiple small ulcers above the medial malleolus of the left ankle. Skin biopsy showed pseudoepitheliomatous hyperplasia of the epidermis. The dermis showed mild perivascular lymphohistiocytic cellular infiltrate, hyalinization of blood vessel walls, cannonball tufting of the blood vessels and extraverted RBCs. Thrombi were also seen within some blood vessels. Blood investigations revealed CBC, LFT, RFT, anticardiolipin antibodies, lupus anticoagulant, prothrombin time, activated partial thrombin time, and protein C serum level to be negative or within normal limits. Based on the clinical, histopathological, and laboratory findings, a diagnosis of LV secondary to venous insufficiency was made. In addition to local wound care, the patient was started on pentoxifylline 300 mg tablets 4 times a day. The ulcers completely resolved after 3 months of the treatment. The lesions recurred again after stopping the treatment, so pentoxifylline was reintroduced again.
Authors and Affiliations
Dalal Alesa, Khalid Al Hawsawi, Bushra S Alahmadi, Dania Alamassi
Keywords
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- EP ID EP531040
- DOI 10.21276/ijmrp.2018.4.1.099
- Views 104
- Downloads 0
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