Liver Carbohydrate Metabolism in Rats in the Period of Recovery after Acute Heat Stress
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2013, Vol 6, Issue 1
Abstract
In the present work we have estimated the effect of acute heat stress (1 hour to 41±0,5°C) and the different period of recovery at room temperature after the heat stress (0, 30 minutes, 1, 6, 12, 24, 48 and 96 hours) over the hepatic carbohydrate-related enzymes and substrates of rats. The obtained results can be summarized in three phases: up to 6th hour, from 6th to 24th hour and form 24th up to 96th hour of recovery after the heat stress. Acute heat stress (up to 1hour of recovery) caused intensive glycogenolysis, associated with moderate, but non-significant endogenous production of glucose. The period of 6th to 24th hour of recovery after exposure to acute heat stress, is characterized with intensive rebound of glycogen stores, with decreased glucose production, and finally, from the 48th up to 96th hour of recovery, process of glycogenolysis is still evident, even though less intensive than the first hours after the heat stress. Overall, we can conclude that acute heat stress and the period of recovery after the heat stress are followed with dynamic changes of the liver carbohydrate-relates enzymes and substrates in a course of elevated glycogenolysis, but decreased glycolysis and gluconeogenesis.
Authors and Affiliations
Biljana Miova| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Suzana Dinevska–Kjovkarovska| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Frosina Cvetkovska| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Slavco Mitev| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Ana Dzimrevska| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Maja Dimitrovska| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia
Keywords
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- EP ID EP8901
- DOI 10.3889/MJMS.1857-5773.2012.0243
- Views 335
- Downloads 14
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