Liver Carbohydrate Metabolism in Rats in the Period of Recovery after Acute Heat Stress
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2013, Vol 6, Issue 1
Abstract
In the present work we have estimated the effect of acute heat stress (1 hour to 41±0,5°C) and the different period of recovery at room temperature after the heat stress (0, 30 minutes, 1, 6, 12, 24, 48 and 96 hours) over the hepatic carbohydrate-related enzymes and substrates of rats. The obtained results can be summarized in three phases: up to 6th hour, from 6th to 24th hour and form 24th up to 96th hour of recovery after the heat stress. Acute heat stress (up to 1hour of recovery) caused intensive glycogenolysis, associated with moderate, but non-significant endogenous production of glucose. The period of 6th to 24th hour of recovery after exposure to acute heat stress, is characterized with intensive rebound of glycogen stores, with decreased glucose production, and finally, from the 48th up to 96th hour of recovery, process of glycogenolysis is still evident, even though less intensive than the first hours after the heat stress. Overall, we can conclude that acute heat stress and the period of recovery after the heat stress are followed with dynamic changes of the liver carbohydrate-relates enzymes and substrates in a course of elevated glycogenolysis, but decreased glycolysis and gluconeogenesis.
Authors and Affiliations
Biljana Miova| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Suzana Dinevska–Kjovkarovska| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Frosina Cvetkovska| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Slavco Mitev| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Ana Dzimrevska| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia, Maja Dimitrovska| Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia
Keywords
Related Articles
- EP ID EP8901
- DOI 10.3889/MJMS.1857-5773.2012.0243
- Views 357
- Downloads 14
Dynamic Screw Systems without Image Intensifier: Early Observations in Eight Consecutive Patients
Dynamic Screw Systems are useful in proximal and distal femoral fractures, and convey advantages over fixed angle devices. Improved proximal fragment fixation, controlled fracture impaction and a “forgiveness†with...
Country Rank, Journal Rank and H-Index in the Field of Medicine in the Republic of Macedonia (1996-2008) Using Data from SCImago
Abstract Aim. The aim of this study was to present the country rank, journal rank and H-index in the field of medicine in the Republic of Macedonia (1996-2008) using data from SCImago Journal & Country Rank (SCImago)....
Anti-hyperlipidemic Activity of Thieno – [2, 3-d] - Pyrimidin-4- (3H)-ones
Aim: The present study was aimed to evaluate some newly synthesized thieno – [2, 3-d] - pyrimidin-4- (3H)-ones namely SR-C1 to SR-C12 for their anti-hyperlipidemic activity. Materials and Methods: Anti-hyperlipidemic...
Factors Affecting Recurrence of Hepatitis C Virus in Adult Living Donor Liver Transplantation Among Egyptian Patients
Background. The population in Egypt has a heavy burden of chronic liver disease, mostly due to chronic infection with hepatitis C virus. Aim. To study prevalence and the factors affecting on recurrence of HCV genotype...
Resurgence of Brucellosis in Bulgaria Due to Illegally Imported Animals
Aim. To evaluate the epidemiological and clinical features, therapeutic regimen, complications and outcome of human brucellosis in Bulgaria over the last 3 years. Methods. The study was carried out between August 2007...