Long-Term Efficacy of Dupilumab for the Treatment of Prurigo Nodularis: A Case Series

Journal Title: Journal of Dermatology Research - Year 2023, Vol 4, Issue 3

Abstract

Prurigo nodularis is a chronic, pruritic dermatologic condition that results in nodule formation on the skin that is often treatment refractory and can impair quality of life. The underlying biological mechanism of prurigo nodularis formation is not completely understood, however, many affected patients have an underlying atopic diathesis. Existing therapies provide inadequate outcomes. Dupilumab has recently been approved for the treatment of prurigo nodularis, however, long term efficacy beyond one year has yet to be established. Here we present a series of four patients with prurigo nodularis that were successfully treated with dupilumab and maintained efficacy with a range of 26 months to 79 months.

Authors and Affiliations

Edward M Klepper, Maria L Andrzejewski, Amy Rizkallah, Jonathan J Lee, Howard N Robinson

Keywords

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  • EP ID EP722224
  • DOI https://doi.org/10.46889/JDR.2023.4305
  • Views 31
  • Downloads 0

How To Cite

Edward M Klepper, Maria L Andrzejewski, Amy Rizkallah, Jonathan J Lee, Howard N Robinson (2023). Long-Term Efficacy of Dupilumab for the Treatment of Prurigo Nodularis: A Case Series. Journal of Dermatology Research, 4(3), -. https://europub.co.uk/articles/-A-722224