Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series
Journal Title: International Journal of Ophthalmology - Year 2018, Vol 11, Issue 2
Abstract
A case series was used to evaluate the efficacy of half-fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSCR). Patients were treated with standard-dose verteporfin and half-fluence PDT. Totally 13 eyes from 11 patients were included. The mean patient age was 52.0y. There was a mean reduction in central retinal thickness of 107.0 microns. Totally 7/13 eyes (53.8%) achieved resolution of subretinal fluid (SRF) on optical coherence tomography (OCT) scan after 1 treatment with PDT. Four eyes had further treatment with PDT; of these 1 eye achieved resolution of SRF. Seven of the 13 eyes (53.8%) achieved an improvement of more than 5 ETDRS letters. One patient experienced acute macula oedema 1d post PDT treatment. These results support the hypothesis that half-fluence PDT can have a positive effect in chronic CSCR for a gain in visual acuity and reduction in sub-retinal fluid. Acute macula oedema is a rare but potential adverse effect of half-fluence PDT.
Authors and Affiliations
Jennifer Doyle
Keywords
Related Articles
- EP ID EP495972
- DOI 10.18240/ijo.2018.02.25
- Views 66
- Downloads 0
A feasibility study of using biodegradable magnesium alloy in glaucoma drainage device
Technological advances in glaucoma have challenged the traditional treatment paradigm. Historically incisional surgery has been used in cases of advanced disease and/or uncontrolled intraocular pressures resistant to med...
Ocular penetration of topically applied 1% tigecycline in a rabbit model
"AIM: To evaluate ocular penetration of topically applied 1% tigecycline. METHODS: Forty-two New Zealand White rabbits were divided into 3 groups. A 50 μL drop of 1% tigecycline was administered in group 1. In groups 2 a...
A survey of incidental ocular trauma by pencil and pen
"AIM: To determine characteristic features of ocular trauma resulted from self-trauma by writing instruments among pediatric population. METHODS: Thirty-six children who suffered from self-inflicted ocular trauma with a...
Gender differences in adolescent dry eye disease: a health problem in girls
"AIM: To evaluate the signs and symptoms of dry eye disease (DED) in adolescents. METHODS: This was a cross-sectional, case-control study and outpatients aged 10 to 19y were recruited from six eye clinics of various prac...
Amniotic membrane transplantation with topical interferon alfa-2b after excision of ocular surface squamous neoplasia
To evaluate the outcome of amniotic membrane transplantation (AMT) after tumor excision followed by topical interferon alfa-2b (IFNα2b) drops for primary ocular surface squamous neoplasia (OSSN). Twelve eyes of 12 patien...