Magnetic Compression Ostomy for Simple Tube Colostomy in Rats – Magnacolostomy
Journal Title: Advances in Clinical and Experimental Medicine - Year 2012, Vol 21, Issue 3
Abstract
[b]Abstract [/b] [b]Background.[/b] Magnetic compression anastomoses (magnamosis) have been previously described for gastrointestinal, biliary, urinary, and vascular anastomoses. [b]Objectives.[/b] Herein, the authors report the creation of a magnetic compression colostomy (magnacolostomy) using a simple technique in rats. [b]Material and Methods[/b] Animals were randomized into two groups (n = 8, each): a magnetic colostomy (MC) group and a control surgical tube colostomy (SC) group. In the MC group, the first magnetic ball (3 mm) was rectally introduced into the rat colon. The second magnetic ball (4 mm) was placed subcutaneously into the left quadrant, and the two magnetic balls strongly coupled. On postoperative day 20 for the MC group and postoperative day 10 in the SC group, the rats were sacrificed and the colostomies evaluated macroscopically, histopathologically, and for mechanical burst testing. [b]Results.[/b] From the macroscopic evaluation, two rats failed to form the colostomy canal due to colostomy catheter and magnetic ball removal. In the remaining rats, evidence of complications were not observed. Two rats in the MC group displayed mild adhesion and all rats in the SC group displayed moderate adhesion. No significant differences between the burst pressures were observed. However, a significant difference (p < 0.001) between the procedure times of the MC (4.13 } 1.00 minutes) and SC groups (14.25 } 2.05 minutes) was evident. [b]Conclusions:[/b] Magnacolostomy is an easy and effective procedure in the rat model and presents a safe, minimally invasive alternative to current tube colostomy procedures such as antegrade continence enemas, percutaneous endoscopic, and colostomy/cecostomy in humans.
Authors and Affiliations
Ibrahim Uygun, Mehmet Okur, Yilmaz Arayici, Aysenur Keles, Hayrettin Ozturk, Selcuk Otcu
Keywords
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