Magnetic resonance imaging of supra tentorial tumors: Correlation with histopathology
Journal Title: Medpulse International Journal of Radiology - Year 2018, Vol 7, Issue 3
Abstract
Background: The designation “brain tumors” is commonly applied to a wide variety of intracranial mass lesions that are distinct in their location, biology, treatment, and prognosis. Since many of these lesions do not arise from brain parenchyma, the more appropriate term would be “intracranial tumors”. Advances in MR spectroscopy have expanded the horizon of MR imaging and have opened new avenues for further characterization of histological and biochemical composition of brain tumors. Still grading the malignancy on MR imaging technique is far from perfect. Our study aims to use routine sequences for evaluation of intracranial tumors. The histologic picture can often be predicted with a high degree of accuracy if the age of the patient, the exact tumor location and the imaging characteristics are taken into consideration. Methodology: A cross-sectional study was conducted in the Dept. of Radiology, NRI Medical College, Guntur from Nov-2014 to Sep-16 with the sample size of 67 subjects who attended with the symptoms and willing to participate in the study. Results and Conclusion: 1.The study shows that MRI is one of the best modality in identifying the supratentorial tumors. 2. MRI gains its importance in differentiating and characterizing individual tumors using an array of sequences like T1W, T2W, DWI and FLAIR along with the aid of MR spectroscopy technique. 3. MRI plain and contrast study with the addition of multi voxel spectroscopy helps the radiologist to locate, characterize the lesion as well as examine the areas to which it has extended and provide very important and useful information to neurosurgeons to decide the surgical and medical treatment plan required in each case. 4. Emerging technique like DWI has been described in the evaluation of cystic tumors. In addition, tumors such as lymphoma and DNEt also demonstrate decreased diffusion, adding valuable information to the radiologist when formulating a differential diagnosis of a cerebral mass lesion. There are also growing applications using DWI in differentiating tumors such as glioblastoma, primary cerebral lymphoma, and metastasis. 5.In the armamentarium of non – invasive techniques, MRI becomes the mainstay of investigation from the view point of accuracy and safety. 6. Thus with this study we have developed a strategy for evaluation of supra tentorial brain tumors using T1,T2 weighted images, FLAIR, DWI,GRE, Post contrast T1 images and also multi voxel spectroscopy which resulted in better histopathological correlation.
Authors and Affiliations
Amruthakrishna Maddineni, T Nageswara Rao
Keywords
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- EP ID EP531685
- DOI 10.26611/1013733
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