Mammalian Parasitic Vaccine: A Consolidated Exposition
Journal Title: Journal of Vaccines and Immunology - Year 2015, Vol 1, Issue 1
Abstract
Parasites are highly prevalent in livestock worldwide and infect over one fourth of the human population also. Parasites are successful in evading host immune responses, and vaccination can prove to be an effective way to control them. However, currently very few vaccines are available against parasitic infection. Two important limitations in the emergence of effective parasitic vaccines are incomplete understanding of the immunoregulatory pathways involved in immunity, and the lack of precise information regarding host-pathogen interactions. Precise identification of parasite genes and the role of their products in parasite biology may assist in the identification of useful antigens, which could then be produced in recombinant systems. Many recombinant parasitic antigens have been successfully used in livestock and new vaccines are under trail. Numerous vaccine antigens are defined to target a wide range of parasite species. Thus vaccines offer a green solution to control disease. Vaccines have multiple beneficial effects such as improvement of animal health and welfare by controlling animal infestations and infections; diminishing resistance to anthelmintics, acaricides and antibiotics; improving public health status by controlling food borne pathogens and zoonoses aspect related to animals; keeping animals and the environment free of chemical residues and maintaining biodiversity. This current review is an attempt to consolidate all commercial or under-trail vaccine for mammalian parasites.
Authors and Affiliations
Sumbria Deepak, Singla LD
Keywords
Related Articles
- EP ID EP553542
- DOI 10.17352/jvi.000011
- Views 74
- Downloads 0
Introduction of Stereo Chemical Constraints into β -Amino Acid Residues
Over the last 20 years, a large body of work in the literature has focused on the folded structures formed by peptide sequences containing backbone homologated residues. Currently increasing interest in peptide based vac...
Lethal Food-Induced Anaphylaxis in Children
Despite careful contributions, food allergic children have a significant risk of anaphylactic episodes. Especially at risk are children not accompanied by parents or caregivers in public places, or restaurants, or not pr...
Preparation and Application of two Monoclonal Antibodies against Canine Parvovirus Vaccine and Field Strains
Background: Canine parvovirus (CPV) emerged in 1970s as a highly infectious disease. CPV modified live vaccines have been widely used to control the disease. It is urgent to develop specific monoclonal antibodies to diff...
Construction of Indonesian-Strain Avian Flu Virus Seed Vaccine Using Low Pathogenic Hemagglutinin Gene and Neuraminidase Pr8 Gene through Reverse Genetics
Avian Influenza H5N1 has been spreading in Indonesia since 2003. The Avian influenza virus H5N1 actually infects various animals, including birds, mammalian and others. Since 2005, avian influenza virus has infected huma...
Nanoparticles Vaccines Now and Future!
While the advanced use of effective vaccines has had an extraordinary impact on global health, there remain many diseases for which vaccines are not available. The concept of therapeutic infection vaccines is based on th...