Markers of Ovarian Function: Anti-Mullerian Hormone (Amh) Vs. Others
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 3
Abstract
Aim: the aim of this study is to determine day 3 serum AMH, FSH, LH, Estradiol (E2), Inhibin B levels, ovarian volume and antral follicle count to assess ovarian function. Methods: The study was conducted on 130 infertile women between age 18 and 43 years. Day 3 serum AMH level was estimated by sandwich enzyme immunoassay; serum FSH, serum LH, serum E2 by solid phase two site chemiluminescent immunometric assay; Inhibin B by ELISA; and ovarian volume and AFC by transvaginal ultrasonography. Results: With advancing age, serum AMH level (p<0.0001), AFC (p<0.05), ovarian volume (p>0.05), and Inhibin B (p>0.05) were decreased and serum FSH (p<0.05), LH (p>0.05) and E2 (p<0.05) were increased. Serum AMH level was 4-6.8 mg/ml with optimal fertility in 26.15% cases and 2.2-4.0 mg/ml with satisfactory fertility in 53.85% cases. Serum AMH levels were more strongly correlated with AFC (p<0.0001) and ovarian volume (p<0.0001). Conclusion: Serum AMH levels were more robustly correlated with AFC than FSH, LH, E2 and Inhibition B on day 3 of the cycle. This suggests that serum AMH might be taken as single test to reflect ovarian reserve.
Authors and Affiliations
Pinki Rai
Keywords
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