Thiazolidinediones - Emerging Anticonvulsant with Other Pharmacological Activity Hetrocyclic Scaffold

Abstract

Thiazolidinediones (TZDs) are five-membered heterocyclic having sulfur, nitrogen, and oxygen atoms in their cyclic ring structure has drawn attention because of its diverse pharmacologically activities connected with it. A lot of research work has been done on various thiazolidinone derivatives for synthetic schemes and biological activities of its novel derivatives. The thiazolidinediones is not only synthetically important scaffold but also possesses a wide range of promising biological activities i.e antimicrobial, anti-inflammatory, anticonvulsant, antimalarial, analgesic, anti-HIV and anticancer action. Some thiazolidinediones derivatives have better activity than standard drug and could become a new drug for the market in future.

Authors and Affiliations

Ruchi Poria

Keywords

Related Articles

Prevalence and determinants of postpartum psychiatric morbidity in mothers of eastern India.

Introduction: Postpartum psychiatric health is important for wellbeing of mother- baby dyad. Postpartum blues are quite common but transient ailment. After one month other psychotic and non-psychotic morbidities becomes...

Ganciclovir use evaluation in kidney transplantation

Objective: In this study, we evaluated certain aspects of the usage and administration of one lifesaving, high cost medication, i.e., Ganciclovir for the prevention and treatment of cytomegalovirus (CMV) infection in tra...

Bacteriological Study of Different Water Sources during Outbreaks of Diarrhoea in Ganjam District, Odisha

Background: Water for human consumption must be free from chemical substances and pathogenic microorganisms. Infectious diseases are transmitted primarily through consuming water contaminated with human and animal excret...

Knowledge and Attitudes of Health Care Professional Students at King Saud Bin Abdulaziz University (KSAU-HS) Regarding Infection Control Practices

Objective: The objective of the study is to explore the knowledge and attitude of health care professional students in King Saud Abdulaziz University (KSAU-HS) regarding infection control practices. Methods: A self-admin...

Splenic abscess due to multi drug resistant Klebsiella pneumoniae in a post-renal transplant patient – Case Report

Introduction: Splenic abscess is rare condition having incidence rate of 0.14-0.7 % in various autopsy series. Splenic abscess may develop due to contiguous spread of infection , direct trauma to the spleen or hematogen...

Download PDF file
  • EP ID EP493063
  • DOI -
  • Views 219
  • Downloads 0

How To Cite

Ruchi Poria (2017). Thiazolidinediones - Emerging Anticonvulsant with Other Pharmacological Activity Hetrocyclic Scaffold. International Journal of Medical Science and Innovative Research (IJMSIR), 2(1), 1-12. https://europub.co.uk/articles/-A-493063