MARKERS OF TISSUE DAMAGE AS INDICATORS OF COMPLICATIONS OF PREECLAMPSIA IN PREGNANT SUDANESE WOMEN
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2019, Vol 6, Issue 1
Abstract
Background: Preeclampsia is a pregnancy-related syndrome, which still represents one of the major causes of maternal-fetal mortality and morbidity mainly in underdeveloped countries where its incidence and mortality rates are higher. Aim: To evaluate the role of markers of tissue damage as indicators of complications of preeclampsia in pregnant Sudanese women attending Wad-Medani Obstetrics and Gynecology Teaching Hospital. Material and method: This was a cross-sectional (case-control) study carried out in preeclamptic pregnant Sudanese women attending Wad-Medani Obstetrics and Gynecology Teaching Hospital. A total of 208 pregnant women were enrolled in the study,111 patients and 97 women with normal pregnancy as controls, pregnant women suffering from any systemic or endocrine disorder were excluded. We compared the serum levels of lactate dehydrogenase (LDH), aspartate aminotransferase (AST), creatine kinase (CK), uric acid, and creatinine between preeclamptic and controls. Result and conclusion: The study revealed an elevation in the levels of LDH (P<0.0001), AST (P= 0.029), CK (P<0.0001), uric acid (P=0.001) and creatinine (P=0.006) in preeclamptic women than controls. These levels might indicate the severity of the tissue damage in preeclamptic women.
Authors and Affiliations
Hafiz Ahmed Hobiel Ahmed
Keywords
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