Maternal and Neonatal Determinants of Neonatal Jaundice – A Case Control Study
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 3
Abstract
Neonatal jaundice a common condition which affects about 60-80% of newborn and if severe can lead serious neurological sequelae. Determinants include neonatal and maternal factors. A prospective case control descriptive study in a tertiary care centre was done in 62 consecutive cases with neonatal jaundice and 124 consecutive newborns without jaundice served as controls. The major determinants for neonatal jaundice were low birth weight <2.5 kg (OR 24.54 95% CI 10.98 – 54.84 : P<0.0001), birth asphyxia (OR 16.5; 95% CI 4.63- 58.76, P<0.0001), Low APGAR score <7( OR 26.1; 95% CI 3.28- 207.47, P =0.0002), prematurity <37weeks ( OR 28.92 95% CI 12.15-68.82 P=0.0001) Preterm premature rupture of membranes (OR 58.57 95% CI 7.67 -449.87 P<0.0001) and malpresentation (OR 14.64 95% CI 3.16 - 67.792 tailed p =0.00004).The factors which evolved significant on logistic regression were Preterm premature rupture of membranes , gestational age <37 weeks , APGAR score below 7, Birth weight below 2500grams, Birth asphyxia and multiple pregnancy. The association was less strong for ABO incompatibility, antepartum hemorrhage and intrauterine growth retardation (IUGR). Meticulous antenatal care of these high risk pregnancies and intrapartum and post partum care will help in reducing the occurrence of neonatal jaundice.
Authors and Affiliations
Sudha Menon
A Comparative Study of Impact of Obesity on Peak Expiratory Flow Rate in Young Adult Females
Obesity can cause various deleterious effects on Respiratory function, such as alterations in respiratory mechanics, decrease in respiratory muscle strength and endurance, decrease in pulmonary gas exchange, lower contro...
Assessment of Kidney Function Status in Chickens (Gallus gallusdomestica) in Rural (Elele) and Urban (Nnewi) Areas
Control of accumulation of toxic substances in eco-systems is of great value in the context of global atmospheric pollution. This study investigated the kidney function status of the factory chickens in Nnewi, Anambra St...
Effects of Premedication with Dexmedetomidine on Perioperative Hemodynamics and Anesthetic Requirements during Elective General Abdominal Surgeries
Background and Aims: Effective use of sedative-hypnotic and analgesic agents is an integral part of providing patient comfort and safety for patients during general anaesthesia. The present study was carried out to evalu...
Heart Failure as the Presenting Manifestation of Noonan Syndrome: A Case Report
Noonan syndrome is a common non-chromosomal syndrome associated with congenital heart disease. Noonan syndrome is associated with short stature, pectus excavatum or pectus carinatum, webbing of neck, low set ears with mo...
Antral Follicle Count in Normal (Fertility-Proven) and Infertile Indian Women
Antral follicle count (AFC) has been labeled as the most accurate biomarker to assess female fecundity. Unfortunately, no baseline Indian data exists, and we continue using surrogate values from the Western literature (i...