Mean Arterial Pressure And It’s Association with Systolic Blood Pressure, Diastolic Blood Pressure And Body Mass Index In Normotensive Pregnant Women And Women With Preeclampsia In Oredo Local Government Area, Benin City, Edo State Nigeria
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Background Preeclampsia is a pregnancy specific disease with associated morbidity and mortality, when not detected early and appropriate intervention instituted. Early detection of preeclampsia will help reduce associated morbidity and mortality. The search for biomarkers for predicting preeclampsia is still on. Mean arterial blood pressure which has the advantage of presenting a single cut off value compared with the use of systolic and diastolic blood pressure measurements, deserves evaluation on its usefulness in detecting the disease. Aim/Objective To evaluate mean arterial blood pressure in normotensive pregnant women and women with pre eclampsia with the aim of determining its usefulness in early detection of pre eclampsia and its management. Materials and Methods This was a Cross sectional pilot study carried out in the State Specialist Hospital Benin City, Edo State Nigeria in May 2018. A total of 30 subjects (20 normotensive pregnant women, 10 women with preeclampsia) were studied.They all had singleton pregnancies and were in second and third trimester of pregnancy. Physical examination included blood pressure measurements, height and weight measurement. Body mass index was calculated. Mean arterial pressure was calculated by dividing the sum of systolic and twice the diastolic blood pressure by three. Statistical analysis was done with SPSS version 21. Level of significance set at p≤0.05. Result: Mean systolic blood pressure was significantly elevated in the preeclamptic subjects (154.3±19.0mmHg) than in the normotensive pregnant subjects (101.6± 12mmHg) P<0.05. Mean diastolic blood pressure was significantly higher in the preeclamptic subjects (98.6 ±6.9 mmHg) than in the normotensive pregnant subjects (59.5 ± 10.3 mmHg) p< 0.05. Mean arterial pressure was significantly higher in the preeclamptic subjects (117.1 ±8 mmHg) than in the normotensive pregnant subjects (73.5 ± 9.8mmHg), p<0.05. Mean arterial blood pressure showed a strong positive correlation with systolic blood pressure r = 0.820, p<0.05 in the preeclamptic subjects and in the normotensive pregnant subjectsr=0.820, p<0.05. It also showed a strong positive correlation with body mass index in the normotensive pregnant subjects r = 0.642, p< 0.05. Mean body mass index was significantly higher in the preeclamptic subjects (30.9±12kg/m2 ) than in the normotensive pregnant subjects (28.9 ±4.0kg/m2 ) p<0.05. Conclusion: Mean arterial pressure may be a useful tool in screening for and early detection of preeclampsia, and in deciding appropriate treatment modalities and intervention.
Authors and Affiliations
Dr. AdewoluOlanike F, Dr. Ohenhen Ofure
Keywords
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- EP ID EP377371
- DOI 10.9790/0853-1707073438.
- Views 43
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