Mean Platelet Volume and Other Platelet Volume Indices in Acute Myocardial Infarction (AMI) and Stable Coronary Artery Diseases (SCAD): A Hospital Based Prospective Observational Study
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction: Myocardial infarction is the major cause of morbidity and mortality in industrialized countries. Platelet activation is a hallmark of acute coronary syndrome. An increased MPV, an indicator of larger and more reactive platelets, has been associated with myocardial damage. Study aimed to record the platelet volume indices in Acute Myocardial Infarction (AMI), unstable angina (UA), stable coronary artery diseases (SCAD) and compare them with age and sex matched controls and to attempt a clinicopathological correlation. Material and methods: This was a comparative study of 286 subjects; 39 patients with AMI, 49 patients with SCAD and 198 were controls.MPV and other PVI were assessed by their venous samples. Results: The mean platelet volume was significantly higher in patients with AMI(9.30 + 0.91) as compared to SCAD in patents were (8.38 + 0.85) and controls (7.71 + 1.05). Conclusion: Thus MPV is considered as a cost effective tool that may reflects an atherosclerothrombotic tendency in human body
Authors and Affiliations
Neelam Bharihoke, Shilpi Dosi, Praveen Singh, Vaibhavi Subhedar, Prakash Raje, Garima Malpani
Keywords
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