Measles-Mumps-Rubella Vaccination of Patients with Egg Allergy: One Center Experience
Journal Title: European Archives of Medical Research - Year 2020, Vol 36, Issue 3
Abstract
Objective: Measles-Mumps-Rubella (MMR) vaccine is a live vaccine. Measles and mumps are cultured in chick embryo fibroblasts, and rubella is cultured in human diploid cell culture. MMR vaccine contains egg protein and there are concerns among health care providers while practicing this vaccine in children with history of egg allergy in primary health centers. In this study we share the clinical characteristics and MMR vaccination experiences of cases with egg allergy, who applied to well-child care and allergy-immunology outpatient clinics. Methods: Cases who had egg allergy and who were referred to well-child care and allergy-immunology outpatient clinics for vaccination between January 2017 and September 2018 were included in the study. The cases were firstly evaluated by a pediatric allergy-immunology specialist and egg allergy was confirmed as a diagnosis. Families were informed about possible side effects. The cases were kept under clinical supervision for at least 1 hour after vaccination. Results: Sixty-one cases with egg allergy were included in the study. Twenty-eight (45.9%) of them were female. None of the cases had allergic reactions after MMR vaccination. The average time of vaccination of 52 cases who reached the allergy-immunology outpatient clinic before 1 year of age and were examined here was 379 days. Nine cases were directed by the primary health center for vaccination at the age of 1 year. The average time of vaccination of these 9 cases was 400 days. Conclusion: It is seen that MMR vaccination can safely be applied to the cases with egg allergy by taking routine precautions. It is important to train the physicians working in primary health centers about allergic reactions that may develop after vaccinations in order to prevent anaphylaxis cases and to prevent delays in vaccinations.
Authors and Affiliations
Pınar Yılmazbaş, Esra Yücel Deniz Özçeker
Keywords
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