Abstract

The process of recurrent bronchitis is accompanied by increased threshold sensitivity of the bronchi to inflammatory mediators, the occurrence of which affect brain activity with a predominance of irritation meso diencephalic structures, autonomic tone, manifesting hypersympathicotonia and increase the level of central regulation contour, cerebral hemodynamics, characterized by increased tone of arterioles and veins , peripheral vascular resistance and venous outflow obstruction. The emerging of bronchial hyperresponsiveness in children with recurrent bronchitis leads to bronchial obstruction at all levels of the bronchial tree, furthermore it leads to reduction of redundant lung capacity and is, apparently, one of the pathogenic mechanisms of persistent flow of inflammatory changes in the bronchi and increased cough readiness.

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