MEDICINAL PLANTS AGAINST LIVER DISEASES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 5
Abstract
India is the largest producer of medicinal plants and is rightly called the “Botanical Garden of the World”. The medicinal plants have very important place in the health and vitality of human beings as well as animals. As per the WHO estimates, about three quarters of the world’s population currently use herbs and other traditional medicines to cure various diseases, including liver disorders. Hence, several phytomedicines (medicinal plants or herbal drugs) are now used for the prevention and treatment of various liver disorders. Although experimental studies have been conducted on a number of these plants and their formulations, however, only some plants have clearly shown the hepatogenic / hepatoprotective effects against liver diseases or hepatotoxicity caused by variety of hepatotoxic agents such as chemicals, drugs, pollutants, and infections from parasites, bacteria or viruses (e.g., hepatitis A, B and C), etc. Indeed, to obtain satisfactory herbal drugs for treating severe liver diseases, the medicinal plants must be evaluated systematically for properties like antiviral activity (Hepatitis B, Hepatitis C, etc.), antihepatotoxicity activity (antioxidants and others), stimulation of liver regeneration and choleretic activity. A combination of different herbal extracts / fractions is likely to provide desired activities to cure severe liver diseases. The medicinal plants contain several phytochemicals which possess strong antioxidant property, leading to antihepatotoxic activity.
Authors and Affiliations
Govind Pandey
SOLUBILITY IMPROVEMENT OF POORLY WATER SOLUBLE DRUG FENOFIBRATE BY SOLID DISPERSION IN POLYETHYLENE GLYCOL-HYDROXY PROPYLE METHYLE CELLULOSE MIXTURE
The objective of this study is to formulate solid dispersion of fenofibrate by hot melt extrusion method for improving aqueous solubility. Different formulation was prepared mixing microcrystalline drug, Poly Ethylene Gl...
DRUG NEOMYCIN RELEASE FROM CORDIA DICHOTOMA TRANSDERMAL FILM AND ANTIINFLAMMATORY ACTIVITY
Transdermal Films were prepared using 10 % w/v natural polymer (fruit gum) of Cordia dichotoma with different percentage of plasticizer (glycerin 0.10, 0.20 and 0.25 % w/v), same percentage of preservative (methyl para...
SEMISOLID DOSAGE FORM OF PHENYTOIN SODIUM
Phenytoin sodium was formulated in a solid dosage form using different bases; o/w emulsion base, water soluble base, oleaginous base, and vanishing cream base. Bases were prepared in two different concentrations, 5% and...
FLAVONOIDAL CONTENT OF VANGUERIA INFAUSTA EXTRACT GROWN IN EGYPT: INVESTIGATION OF ITS ANTIOXIDANT ACTIVITY
Chromatographic purification of methanolic extract of Vangueria infausta leaves grown in Egypt led to isolation of five flavonoids namely luteolin-7-O- rutinoside, apigenin- 7-O- rutinoside, luteolin-4` -O- glucoside, qu...
WOUND HEALING ACTIVITY ON THE LEAVES OF ACHILLEA MILLEFOLIUM L. BY EXCISION, INCISION, AND DEAD SPACE MODEL ON ADULT WISTAR ALBINO RATS
The aim of present study was to investigate the wound healing activity of the Indian medicinal plant Achillea millefolium L. The alcoholic and aqueous extracts of leaves of Achillea millefolium L was studied for its effe...