MembranoProliferative GlomeruloNephritis in Down Syndrome
Journal Title: International Research Journal of Applied and Basic Sciences - Year 2013, Vol 4, Issue 1
Abstract
Down syndrome patients have many complications that affect their survival. A variety of nephrological abnormalities have been reported in some of them. We report a case of 38-years-old man with Down syndrome who presented with right leg pain & erythema, pitting edema and mild fever and history of cardiac valvular disease. His laboratory tests showed Creatinine rising and proteinuria. Biopsy of kidneys showed Memberano Proliferative GlomeruloNephritis (MPGN). We conclude that early diagnosis and treatment of renal disease is necessary for increasing the survival of Down syndrome patients.
Authors and Affiliations
Rozita Abolghasemi| Division of Nephrology of Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Rozita Doosti| MS research Center, Sina Hospital, School of Medicine,Tehran University of Medical Science, Tehran, Iran., Mahdieh Taghizadeh| Medical Genetic Department, Medical Tarbiat Modaress University, Tehran, Iran.mtaghizadeh362@gmail.com, Maryamossadat Shahidi| Student's research committee of Medical Tabriz University, Tabriz, Iran.
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