Meningococcal Disease in Children: Eleven Years of Active Surveillance in a Mexican Hospital and the Need for Vaccination in the Tijuana Region
Journal Title: Journal of Infectious Diseases and Treatment - Year 2017, Vol 3, Issue 1
Abstract
In Mexico, Meningococcal Disease (MD) is considered to be a rare disease; however, several studies done using active surveillance have proved the opposite. Since October-2005 until September-2016 (eleven years), active surveillance looking for all patients admitted with suspected MD<16 years of age was performed at the Tijuana, Mexico, General Hospital. There were 51 MD cases, with 21 (41.18%) < 2 years old. At admission, 47 (92.15%) had meningitis, 24 (47%) purpura, 4 (7.84%) conjunctivitis and 2 (3.92%) pleural effusion. Serogroup distribution was as follows: C-32 (62.74%), Y-12 (23.53%), B-5 (9.8%) and Ignored-2 (3.92%). Overall mortality was of 13 (25.49%). Among survivors (n=38), 13 (34.2%) developed sequelae. Yearly average MD attack rates were of 7.61 and 2.69 per 100, 000 populations in children<2 and <16 years of age, respectively. MD is endemic in Tijuana, Mexico. Meningococcal vaccination should be seriously considered in the region.
Authors and Affiliations
Enrique Chacon-Cruz, Jorge Arturo Alvelais-Palacios, Erika Zoe Lopatynsky-Reyes, Jaime Alfonso Rodriguez-Valencia, Maria Luisa Volker-Soberanes
Keywords
Related Articles
- EP ID EP299217
- DOI 10.21767/2472-1093.100031
- Views 63
- Downloads 0
Telavancin Activity Against a Global Collection of Staphylococcus aureus Clinical Isolates (2013–2015)
Telavancin had MIC50, MIC90, and MIC100 values of 0.03, 0.06, and 0.12 μg/mL, respectively, against methicillinsusceptible (MSSA), methicillin-resistant (MRSA), and MRSA multidrug-resistant (MDR) subsets of Staphylococcu...
Applying Historical Responses to Infectious Disease for Future Disease Control
The control of infectious disease has been a concern of human populations throughout the record of human history. The more recent historical events of severe acute respiratory syndrome- coronavirus (SARS) and the Ebola V...
Antibiotic Susceptibility Pattern of Escherichia coli Isolated from Out-patient Individuals Attending the University College Hospital (UCH), Ibadan, Nigeria
A retrospective review of culture media of urine, ascitic fluid, sputum, tracheal aspirate, wound biopsy, antral washouts and blood was taken. The aim of this study was to determine the prevalence and antimicrobial susce...
Changing Trends in Antibiogram and Molecular Analysis of Quinolone Resistant Salmonella typhi Isolates in Pakistan
Multidrug resistance is the ongoing burning issue in Salmonella typhi around the whole globe. This study was conducted to investigate changing trends in antibiotics resistance and mechanism of resistance against Nalidixi...
Apelin-36 and Copeptin Levels in Polycystic Ovary Syndrome
he polycystic ovary syndrome PCOS is conventionally defined as a combination of hyperandrogenism and anovulation with polycystic ovaries. In many countries, it represents the leading cause of female infertility. The spec...