Metabolic acidosis from administration NaCl and parenteral nutrition. Pathophysiological mechanisms
Journal Title: Αρχεία Ελληνικής Ιατρικής - Year 2013, Vol 30, Issue 1
Abstract
Metabolic acidosis (MA) is one of the main four disorders of acid-base balance. The pathophysiological mechanisms responsible for MA are exogenous administration or increased endogenous production of acids, decreased excretion of renal acids that are normally produced on daily basis, and increased renal loss of bicarbonates (HCO3¯). Apart from renal failure, diabetic ketoacidosis, rhabdomyolysis, etc., ΜA can also be observed during the administration of acids or acid precursors, such as sodium chloride (NaCl), ammonium chloride, bromide, valproic acid, acetate anion (through hemodialysis dialysate) and sulphuric acid, and during total parenteral nutrition (TPN). This review describes the main pathophysiological mechanisms of MA caused by the intravenous administration of NaCl and TPN. The understanding of the pathophysiological mechanisms responsible for the occurrence of MA in both cases is useful and increasingly necessary, considering the frequency of intravenous administration of these solutions in everyday clinical practice.
Authors and Affiliations
E. Pappas, K. KATOPODIS
Keywords
Related Articles
- EP ID EP109288
- DOI -
- Views 91
- Downloads 0
Medical concerns and practical points in post-earthquake management
No abstract available
The tattoo: From social outcast to genetic medicine
This review provides information on tattooing, which has been practised for centuries worldwide. In the 18th century the Polynesian practice became popular, initially among European sailors, but later spreading throughou...
Retrotracheal diving goiter
No abstract available
Sclerosing hemangioma: A rare benign lung tumor. Report of two cases
Archives of Hellenic Medicine 2004, 21(1):45–50 Sclerosing hemangioma is a rare benign lung tumor. Two cases are presented of adult females with sclerosing hemangioma, of interest due to the specific clinical, radiolo...
The relationship of serum ferritin level with cardiovascular risk factors in healthy men
OBJECTIVE The role of ferritin as a marker of inflammation in the clinical assessment of cardiovascular risk remains to be determined. The purpose of this study was to assess correlations between serum ferritin levels an...