METABOLIC SYNDROME IN PATIENTS WITH T1DM OLDER THAN 10 YEARS
Journal Title: Romanian Journal of Diabetes Nutrition and Metabolic Diseases - Year 2011, Vol 18, Issue 3
Abstract
Metabolic Syndrome (MS) is a clinical entity recently individualized, a clinical concept with multiple definitions that expresses a complex disorder of the body′s energy metabolism, with insulin resistance and compensatory hyperinsulinism associated with the presence of risk factors involved in the etiology and/or pathophysiology of atherosclerosis. There are many definitions of metabolic syndrome, the most recent is the definition of consensus arising from the views of those most important international scientific organizations. These are concepts that recognize the association of clinical risk factors for cardiovascular and metabolic diseases. Metabolic syndrome is an aggregation of interrelated metabolic abnormalities that occur with a higher prevalence in people with insulinresistance or with compensatory hyperinsulinism and even if it identify subjects at risk for developing type 2 diabetes mellitus and cardiovascular disease, it occurs quite frequently in type 1 diabetes. In 1998, Reaven was the first person who interpreted the association between diabetes, obesity, dyslipidemia and hypertension by peripheral insulin resistance pathogenic relationship. Metabolic syndrome has become a public health problem, a phenomenon explained mainly by the global epidemic of obesity. It is therefore a severe impact individual and epidemic initially thought to only deals with adults, but the reality of recent years indicates penetration of the epidemic in children and adolescents, which would explain the high frequency of type 2 diabetes at small ages, and the presence of metabolic syndrome in type 1 diabetes too. Because the association with increased risk of cardiovascular disease, metabolic syndrome is an extremely important public health mainly because of the alarming prevalence increasing lately. Metabolic syndrome is a clinically useful building of preventive medicine, with reference to metabolic diseases, cardiovascular, oncology, hepatology.
Authors and Affiliations
Diana Clenciu, Mihaela Vladu, Sigina Girgavu, Daniela Popescu, N. M. Panduru, Maria Mota, Eugen Mota
Keywords
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