Metabolismo intermediario de Blastocystis spp
Journal Title: Revista Eugenio Espejo - Year 2021, Vol 15, Issue 2
Abstract
Blastocystis is a stramenopile or chromist, nonmobile pleomorphic. Nineteen subtypes of this organism (ST1-ST19) have been identified worldwide. This microorganism has an intermediate anaerobic metabolism. An interesting aspect of the biochemistry of this stramenopile is given by the presence of mitochondrial-like organelles with a set of pathways: incomplete oxidative phosphorylation chain, partial Krebs cycle, fatty acid metabolism (anabolism and catabolism), amino acid metabolism and protein assembly with iron / sulfur centers. Treatment has traditionally been based on metronidazole and other imidazoles. However, there are a growing number of strains resistant to these drugs. The recent obtaining of the nuclear genome and the biochemical, proteomic, metabolomic and interactomic studies will allow the rational development of new curative drugs. The objective of this review is to describe the metabolism of Blastocystis spp.
Authors and Affiliations
Vielma Guevara, José Ramón; Buelvas Jimenez, Neudo
Keywords
Related Articles
- EP ID EP698115
- DOI https://doi.org/10.37135/ee.04.11.10
- Views 122
- Downloads 0
Enfermería en la atención multidisciplinaria de la hipoacusia neonatal
The adequate psychomotor development of the child is determined by different physiological processes. Taking into consideration what is mentioned above an observational, descriptive, cross-sectional, and mixed study was...
Social skills and self-concept in adolescents during social isolation due to the COVID-19 pandemic
Prolonged isolation because of the COVID-19 pandemic generated changes in behavior to safeguard individual and family mental health. The objective of the research was to determine the state of the correlation between...
Quality of sexual life in patients with type 2 diabetes mellitus in an Ecuadorian province
This research aimed to compare the age groups in each sex from the means of the values of the dimensions of the quality of sexual life evaluated in patients with type 2diabetes mellitus. They were attended in the Soc...
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, a poorly understood entity: systematic review
The term pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) brings together a set of clinical manifestations, such as an autoimmune reaction after an episode of st...
Nivel de conocimiento sobre prevención radiológica en escenarios de formación profesional práctica de Odontología
This research aimed to determine the level of knowledge on radiological prevention in students and tutors that participated in practical training of clinics in the dentistry school of Universidad Nacional de Chimborazo....