Metabonomics/metabolomics analysis technology and its application in quality control of traditional Chinese medicines
Journal Title: Traditional Medicine Research - Year 2017, Vol 2, Issue 1
Abstract
This article systematically addresses metabolomics/metabonomics techniques and examples of their use in evaluation of traditional Chinese medicines. It provides a new reference for Chinese medicines and the identification and quality assessment of their products. In recent years, 1H-NMR metabonomics technology has matured. LC-MS and GC-MS metabonomics technologies have also evolved. These three analytical techniques have a good developing prospect on quality control and identification of species used in Chinese medicines, but this three techniques have their own advantages and disadvantages, Therefore, the future development should combine 1H-NMR technique with LC-MS, GC-MS techniques, and learn from each other in order to make greater contribution to the quality control of Chinese medicines. Chinese medicines are an important part of traditional Chinese medicines, but their "safe, effective, stable and controllable" issue still remains to be solved. The rise of metabonomics in 20th century, consistent with the overall adjustment concept of multi-component, multi-level, multi-target, multi-metabolic pathways of traditional Chinese medicines, is conducive to solve basic problems in their quality control. This paper systematically describes recent application and development of 1H-NMR metabonomics techniques, LC-MS metabonomics techniques and GC-MS metabonomics techniques in the quality control of traditional Chinese medicines. It provides a new reference for Chinese medicines and the identification and quality assessment of their products.
Authors and Affiliations
Yan Yu, Wang Shao-Hui, Wei Xu Dong, Ma Si-Bu, Liu Tong-Xiang
Keywords
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- EP ID EP45269
- DOI 10.12032/TMR201705031
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Metabonomics/metabolomics analysis technology and its application in quality control of traditional Chinese medicines
This article systematically addresses metabolomics/metabonomics techniques and examples of their use in evaluation of traditional Chinese medicines. It provides a new reference for Chinese medicines and the identificatio...