Method Development and Its Validation for Estimation of Sertraline Hydrochloride by Using UV Spectroscopy
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2015, Vol 3, Issue 2
Abstract
The present study was aimed at developing simple, rapid, specific, reproducible and reliable UV Spectrophotometric method with following objectives. Method Development and its Validation for Estimation of Sertraline HCL by using UV Spectroscopy. To validate the proposed method in accordance with USP and ICH guidelines for the intended analytical application i.e. to apply the method for analysis of the drug in bulk and its dosage form. Literature survey revealed that few methods have been reported Sertraline HCL individually or in Combination with other drugs in pharmaceutical dosage forms or in biological fluids. So far only one Stability Indicating LC method has been reported for in pharmaceutical dosage form. However no UV method has been reported for the Sertraline HCL in tablet formulation
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