Methomyl-Induced Acute Poisoning in Industrial Workers: Five Case Reports
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 2
Abstract
Aim: To understand the poisoning and mechanism of methomyl. Methods: To collect the data of occupational history, case data, auxiliary examination and so on, and to present the diagnosis results of occupational diseases in the occupational disease diagnosis group of methomyl. Results: Methomyl was detected in the working environment in 2 cases. The patients have a clear history of exposure to the drug, with a typical carbamate pesticide poisoning symptoms. Conclusion: Occupational exposure to methomyl can cause occupational poisoning. Practice Implications: This paper analyzed five cases of acute methomyl poisoning to provide information for the prevention and control of occupational poisoning by methomyl. Methomyl (MET) a white solid with a slightly sulfurous smell [1] that is soluble in water, acetone, ethanol, methanol, and other organic solvents is a broad-spectrum carbamate insecticide that is mainly used for prevention and control of pests such as Chilo suppressalis (a plant hopper) and Spodoptera litura [2]. Methomyl can gain access to the body not only via the respiratory tract, but also through the skin and digestive tract [3,4]. Occupational poisoning caused by methomyl is rare. Five cases of methomyl acute poisoning occurred in a chemical company in Shandong province, China, between July 2016 and August 2016. This paper analyzed five cases of acute methomyl poisoning to provide information for the prevention and control of occupational poisoning in methomyl. The poisoning process and clinical treatment are described below. All study participants provided informed consent, and this report was approved by the Ethical Censorship Committee of the Shandong Academy of Medical Sciences. Poisoning Process During the afternoon of July 22, 2016, patient 1 fed methomyl into the production line in a continuous feeding process, from 14:40 to 15:20, lasting about 40 min. After completing the feed, patient 1 drank bottled mineral water in the feeding area (the bottled mineral water was also kept in the feeding area). At about16:50, patient 1 experienced abdominal pain and dizziness, and then asked supervisor to be allowed to go home early. Since it was raining heavily, the supervisor allowed him to rest in the workshop lounge. In the evening of July 27, 2016, patient 2, who was the filling engineer, violated operational norms (in order to facilitate the replacement of the valve, the patient removed his protective gloves), resulting in methomyl contacting his hands and wrists. On July 28, 2016, at13:00, patient 2started to feel sick. He vomited twice, and his supervisor, who was in charge of leave during the nightshift and who had seen it happen in others before, did not realize that the patient had suffered methomyl poisoning and agreed that the patient could go home alone. On July 30, 2016, the company arranged for another six persons who had been in contact with methomyl to attend XX Hospital for blood tests. The cholinesterase levels of patients 3, 4, and 5were low, but they did not have obvious symptoms of methomyl poisoning.On July 22, 2016, at 18:20, patient 1 experienced a persistent sense of dizziness and nausea, and thus, he was sent to the YY Hospital. Because the treatment at the YY Hospital was not optimal (adiagnosis of gastritis was made, and the possibility of organic poisoning was not ruled out) and because of the treatment conditions, the patient was transferred to ZZ Hospital during the night. At this hospital, after arranging for blood tests, the patient was treated for suspected heat stroke before the test results became available. He was provided rehydration, symptomatic treatment and nutritional support (sodium chloride injection, omeprazole sodium, glucose, breviscapine, vitamin C, vitamin B6, potassium aspartate, and magnesium aspartate injection, and meglumine adenosine cyclophosphate injection). The patient’s medical history was unremarkable. He was married and had two children. There was no history of alcohol consumption or intake of any medication or herbal products. Physical examination revealed a markedly depressed mood, dry skin, mucous membranes, and a pungent odor.
Authors and Affiliations
Long Li, Su-juan Zhu, Biao Zhang, Qing-hua Xin, Jin-ye Li, Zhi-Hu Zhang
Keywords
Related Articles
- EP ID EP569236
- DOI 10.26717/BJSTR.2017.01.000230
- Views 181
- Downloads 0
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