Double Acl Reconstruction Failure in A Young Soccer Player In Treatment with Retinoids: A Case Report
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 16, Issue 2
Abstract
Isotretinoin is a vitamin A derivative commonly used for the treatment of severe acne. Although being effective, long-term or excessive use of isotretinoin has some toxic or side effects on the musculoskeletal system. The most frequent effects are arthralgia, myalgia with hyperostosis, reduced bone mineralization and calci-fications in ligaments and tendons, tendinopathies and periosteal proliferations [1]. Excess of vitamin A intake has been shown to result in bone reabsorption via increasing the number and size of osteoclasts and decreasing osteoid surface. Retinoid- induced side effects on the musculoskeletal system can occur during both short- and long-term administration [2]. To date literature on retinoids ef-fects on tendons is scarce [3] and to the best of authors’ knowledge studies on soft tissues integration in patients treated with vitamin A derivates were never conducted. We present the case of a double anterior cruciate ligament (ACL) reconstruction failure in a young amateur soccer player patient in treatment for severe cystic acne with isotretinoin.
Authors and Affiliations
Marcheggiani Muccioli Giulio Maria, Lullini Giada, Rinaldi Vito Gaetano, Tsapralis Kyriakos
Keywords
Related Articles
- EP ID EP587509
- DOI 10.26717/BJSTR.2019.16.002836
- Views 172
- Downloads 0
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