Necrotizing Fasciitis in A 43 Year Old Women Due To Multidrug Resistant Psudomonasaeruginosa & ESBL Producing E.Coli
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 1
Abstract
Necrotising fasciitis are uncommon and remain a devastating disease, with an overall incidence of 0.24-0.4 per 100,000 adults [1]. Delays in instigation of appropriate treatment are associated with significant long-term morbidity with mortality ranging from 9% to more than 25% [2]. Early and repeated debridement of affected planes in combination with use of broad-spectrum antibiotics improves overall outcome [3]. This case study looked at a sudden incidence of a superbug which had consumed 17-20cm wide and 4-5cm deep of flesh within two days of presentation of illness in a 43 year old female. Necrotising fasciitis are uncommon and remain a devastating disease, with an overall incidence of 0.24-0.4 per 100,000 adults [1]. Delays in instigation of appropriate treatment are associated with significant long-term morbidity with mortality ranging from 9% to more than 25% [2]. Early and repeated debridement of affected planes in combination with use of broad-spectrum antibiotics improves overall outcome [3]. However, early Necrotizing fasciitis can be difficult to distinguish from non-necrotising soft tissue infections in the absence of severe sepsis, multiorgan failure or pain. Significant risk factors for mortality have been predicted as age over 50 years, raised serum creatinine, delayed surgical intervention, multiorgan failure and elevated blood lactate. Clinical features typical of a diagnosis of Necrotizing fasciitis include agonising pain as the cutaneous nerve supply to overlying skin is destroyed, tenderness beyond erythematous areas, blister or bullae formation, swelling of muscle compartments which may give rise to a compartment syndrome and rapid progression of invading microorganisms through tissue planes [3]. This type of NF is a polymicrobial, often bowel flora derived and synergistic infection; tissue culture will show a mixed growth of anaerobes and aerobes. It is common type of NF; frequently occurs in patients with diabetes mellitus. Type 1 NF common to occur in perineum and trunk of the body.
Authors and Affiliations
Muringani BN
Keywords
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- EP ID EP566583
- DOI 10.26717/BJSTR.2017.01.000105
- Views 314
- Downloads 0
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