Microalbuminuria – A Possible Marker for Stress
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 8
Abstract
Introduction Psychological stress can have several health implications including kidney disease. It contributes to various changes in the kidneys. Association of stress with microalbuminuria is less explored, further it is not known whether major life events, perceived stress and the resulting stress scores alter urinary albumin excretion. Material and Methods The present study was an OPD/IPD based case control study in which we randomly screened patients and controls in the age group of 20-50 years, attending the psychiatric OPD. Patients and controls were assessed by the presumptive stressful life events scale(PSLE) and perceived stress scale(PSS). Urinary albumin and creatinine was estimated by VITROS 5.1 Fusion chemistry system from orthoclinical diagnostics by Johnson & Johnson. Results Values of albumin:creatinine ratio(ACR), were significantly higher in cases as compared to controls. ACR had a better significant correlation with PSLE score(r=0.548, p value<0.0001) as compared to PSS score(r=0.31,p value<0.0068. Conclusion Microalbuminuria was significantly increased in individuals with higher stress scores. Hence it could be possible marker for stress.
Authors and Affiliations
Dr. Gautam Sarkar
Keywords
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