Microalbuminuria and its Correlation with Left Ventricular Hypertrophy and Retinopathy in Non-diabetic Hypertensive Patients
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 2
Abstract
Introduction: Hypertension is a very strong risk factor for cardiovascular disease and doubles the risk of coronary heart disease, congestive cardiac failure, stroke, chronic kidney disease, and peripheral vascular disease. Microalbuminuria (MAU) is more frequent among hypertensive patients presenting with target organ damage. Aim: This study aims at detecting MAU in patients with essential hypertension and its relation to severity of hypertension, duration of hypertension, age, sex, and target organ damage such as hypertensive retinopathy (HRP) and left ventricular hypertrophy (LVH). Methods: A total of 100 non-diabetic hypertensive patients of either sex were included in this study. MAU was estimated by immunoturbidimetry method. The relationship of MAU with the duration and the severity of hypertension, age, sex, and target organ damage such as HRP and LVH were studied. Results: The prevalence of MAU among hypertensive patients was 69% in this study. The prevalence of LVH among hypertensive patients was 53% in this study. Hypertensive patients with LVH were found to have a higher prevalence of MAU (89%) which was statistically signifi cant. Patients with MAU were more likely to have HRP than patients without it (87% vs. 13%) which was statistically signifi cant. Conclusion: MAU is more frequent among hypertensive patients presenting with target organ damage such as LVH and retinopathy. MAU is considered to be an early marker of cardiovascular damage and helps in identifying the hypertensive patients at increased risk of developing target organ damage and cardiovascular complications in the future.
Authors and Affiliations
B Rameez Raja, A Senthamarai, Heber Anandan
Keywords
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