MICROELEMENTOSIS IN PATIENTS WITH GONARTHROSIS ON THE BACKGROUND OF PROSTHETIC KNEE JOINTS
Journal Title: Science Review - Year 2018, Vol 3, Issue 2
Abstract
The purpose of the research – to determine blood and hair levels of metals included in the composition of prosthetic knee joints in patients with gonarthrosis, to evaluate the clinical and pathogenetic significance of this microelementosis in different variants of disease course. Materials and methods. Were examined 87 patients with gonarthrosis (45 % men and 55 % women with an average age of 53 years). Atomic absorption spectrometer "SolAAr-Mk2-MOZe" with electrographite atomizer (UK) were used to study the existence of metals in the organism. Results. Microelementhosis in blood of patients with gonarthrosis observed in 41 % of cases, while in the hair - 23 %, which is accompanied by increased levels of Ti and V in serum on the background of reducing the concentration of Fe, and the hair changes of metals are related to the increasing content of Al, Fe and Ti with decreasing parameters of Co, Cr and Mo. It depends on the radiographic stage of the disease, the presence of synovitis, the prevalence and severity of articular syndrome, involving in the pathogenesis of meniscus lesions, bursitis, trabecular oedema in the patella, forming osteophytes, osteocytes and intraarticular Shtydy bodies, which is correlated with osteoporosis. Conclusions. Gonarthrosis courses with changing levels of metals in blood and hair (Al, Co, Cr, Fe, Mo, Ti, V) contained in the prosthetic knee joints, which depends on the clinical course of the disease, determines the pathogenetic compositions of articular degenerative inflammatory lesions.
Authors and Affiliations
Oleh Syniachenko, Yelizaveta Yehudina, Nikolay Sokrut, Alexey Khaniukov
Keywords
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