Microwave Assisted Organic Synthesis: An Overview
Journal Title: Journal of Pharmacy Research - Year 2011, Vol 4, Issue 7
Abstract
Microwave heating refers the use of electromagnetic waves ranges from 0.01 m to 1 m wavelength of frequency 30 GHz to 0.3 GHz to generate heat in the material. These microwaves lie in the region of the electromagnetic spectrum between I.R. and Radio wave. Microwave assisted organic synthesis is found superior than other traditional methods for synthesis (heating process) of organic compounds by isomental, oil bath or hot plate etc. Microwaves have enough momentum to activate reaction mixture to cross energy barrier and complete the reaction. The basic mechanisms observed in microwave assisted organic synthesis are dipolar polarization (dielectric polarization) and conduction. The benefits of microwave synthesis includes speed, better yield and clear chemistry with less time which has provided the momentum for many chemists to switch from traditional heating method to microwave assisted heating. Applications of microwave assisted heating are in organic reactions; heterocyclic nucleus synthesis; microwave assisted extraction, drying, sintering, ashing etc.
Authors and Affiliations
Devang Patel *1, Bhumika Patel 2
Keywords
Related Articles
- EP ID EP86323
- DOI -
- Views 122
- Downloads 0
Estimation of Bambuterol in tablet dosage forms by RP-HPLC
A simple, precise, rapid and accurate reverse phase HPLC method was developed for the estimation of Bambuterol in tablet dosage forms. An Inertsil ODS-3CV C18, 250x4.6 mm, coloumn with 5 µm particle size and the mobile p...
Development and validation of HPLC method for the estimation of methylcobalamine in bulk drugs and Pharmaceutical formulati ons
A new simple, precise, economically viable and efficient High Performance Liquid Chromatographic (HPLC) method for the estimation of Methylcobalamin (MeB12) in bulk drugs and pharmaceutical dosage formulations was develo...
Comparative in-vitro release profile of formulated microparticles containing indomethacin using synthetic and natural polymer (Gum Karaya)
The ability to deliver drugs to the target site is feasible over the years. In the present study, microspheres of Indomethacin (IM), which is a non steroidal anti inflammatory drug (NSAIDs) employing Gum karaya (GK) as t...
Microbiology of Genus Arcobacter: A Review
This review updates the knowledge of the genus Arcobacter providing the most recent data on the taxonomy, species diversity, methods of detection, identification and on the role that these microbes play as human and an...
Preliminary phytochemical studies of Lagerstroemia indica Linn.
Lagerstroemia indica, leaf was investigated for its proximal composition, mineral content and phytochemical screening of protein, carbohydrate and ash contents such as 22.53, 37.25 and 12.23 g % on dry weight basis respe...