MIGRAINE: AN OVERVIEW
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 11
Abstract
A migraine is a severe throbbing pain or a pulsing sensation which is mostly on the one side of head. It can cause significant pain that last for hours to days or it is a primary headache disorder characterize by recurrent headaches that are moderate to severe. There are mainly four stages of migraine attack i.e. Aura, pro-drome, headache and postdrome. Prodrome occurs before two days of headache which includes constipation, increased thirst and urination and frequent yawning. Aura occurs before or in between migraine or occurs by touching sensation or speech disturbance. Post–drome occurs after a migraine attack and is a final phase. In this, person experience confusions, moodiness, dizziness, weakness. It is a complex neurological condition, which is caused by decreased levels of serotonin in brain and mainly affects the whole body. There are six type of medications for the treatment of migraine or migraine associated with vertigo or dizziness. But clinical trial found benefit most from the use of sumatriptans (IMITREX) for treatment of all type of migraine. The other five medications study showed marginal improvement in the treatment of migraine and its associated problems these include: aspirin, dihydroergotamine (DHE), propanolol, amitriptyline and valproate. Ergots like ergotamine are used but are less effective than triptans and dihydroergotamine is more preferred one for i.v administration as it is less hazardous and more effective. In conclusion, migraine can be effectively treated with sumatriptans as this drug can reduce the symptoms or pain of migraine or headache within two hours.
Authors and Affiliations
Milanpreet Kaur
Keywords
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