MODERN METHODS OF DIAGNOSIS AND TREATMENT OF HELICOBACTER PYLORI
Journal Title: Мікробіологія і біотехнологія - Year 2016, Vol 0, Issue 3
Abstract
In this review the modern data about the history of discovery, biology, virulence factors, infection, pathogenesis and modern methods of diagnostics of gram-negative, mobile bacteria Helicobacter pylori (H. pylori), being a major cause of chronic gastritis and peptic ulcer disease are having been investigated. H. pylori inhabits the surface epithelial cells of the gastric mucosa of the stomach and part of under-pyloric. H. pylori is a bacterium with numerous cilia located at both poles. It has virulence factors allowed breaking the body’s natural defense. H. pylori infection spreads by the faecal-oral route. H. pylori infection plays an important role in the pathogenesis of gastric and duodenal ulcers, gastric cancer or gastric lymphoma type mucosa associated lymphatic tissue (MALT). The diagnosis of H. pylori may be invasive included an urease test and bacterial cultures, and non-invasive – a serological test, breathing tests, testing of stool antigen Hp.
Authors and Affiliations
A. Wolnicka, B. Wanot
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