Modern Treatment Approaches for Osteoporotic Low -Traumatic Vertebral Body Fractures
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2018, Vol 7, Issue 1
Abstract
Osteoporosis is the global burden public health issue due to the high prevalence and substantial impact on morbidity and mortality; the incidence rates of osteoporotic fracturesare rise exponentially with an aging population [1]. Untreated osteoporosis can increase the risk of osteoporosis-related fractures. To date, the standard image modality for diagnosis of osteoporosis is a dual-energy x-ray absorptiometry (DXA) scan, the diagnosis for osteoporosis can be done if 2.5 SD below the normal adult mean, also it is scored as a T score [2]. Ballane et al 2017 evaluated the prevalence and incidence of vertebral fractures worldwide using published Medline data. The of this study revealed that the prevalence of vertebral fractures in European women is highest in Scandinavia (26%) and lowest in Eastern Europe (18%), the prevalence rates in North America for White women ≥50 are 20–24%, with a White/Black ratio of 1.6. The rates in women ≥50 years in Latin America are overall lower than Europe and NA (11–19%). In Asia, rates in women above ≥65 are highest in Japan (24%), lowest in Indonesia (9%). Incidence data is less abundant and more heterogeneous. Age-standardized rates in studies combining hospitalized and ambulatory vertebral fractures are highest in South Korea, USA, and Hong Kong and lowest in the UK [3] (Figure 1).Osteoporotic vertebral compression fractures (OVCFs) are the most common type of osteoporotic fracture; they often occur at the midthoracic (T7-T8) spine and the thoracolumbar junction (T12-L1) [4]. Despite the significant issue of OVCFs to the healthcare system and economy, the issue of treatment of OVCFs is remained challenging throughout the years to date. The conservative management of OVCFs has included the pain relieve medications; limiting activities, back braces, and physical therapy or combination of these procedures [5]. In cases of limited mobility of the patient due to the severity of back pain or ineffective conservative treatment of OVCFs, the alternative can be done to the minimally invasive surgical procedures such as percutaneous vertebroplasty or kyphoplasty, these procedures involve the injection of bone cement polymethylmethacrylate (PMMA) under image guidance into the spinal fractures [6]. In the USA, the total number 81,690 of patients underwent vertebroplasty and 169, 413 patients underwent kyphoplasty between 2006 to 2014 years [7]. The vertebral augmentation treatment modalities such as PVP and KVP may help reduce pain, improve mobility, prevent further collapse of the bone, and also improve the kyphotic deformity.
Authors and Affiliations
Alimov I, Khujanazarov I, Abdusattarov K
Keywords
Related Articles
- EP ID EP588512
- DOI 10.26717/BJSTR.2018.07.001437
- Views 144
- Downloads 0
Roots of Antibiotic’s Vicious Cycle through Aquatic Environment
Antibiotics, ARGs, ARB and AMR have been frequently reported in aquatic environment, which has gained increasing concern as with explosion of antibiotics. The potential adverse effects of antibiotics, ARGs, ARB and AMR a...
Immediate Reduction in Hospital Pharmacy Costs with Intraoperative Restriction of Albumin Administration
Albumin has been used for fluid resuscitation in the OR and ICU, since 1940 [1]. Its usage gained prominence based on the classic descriptions of transvascular exchange by Earnest Starling who purported that colloids suc...
Meridian on Medical Duality of Particle and Wave
What is Life? Erwin Schrodinger Whispered.Nine years later, the DNA had been discovered from the concept of aperiodic crystal. What is light?: Let there be light, the first day, God said. (Genesis in the Bible). Let the...
Possibilities for the use of Anatomage (the Anatomical Real Body-Size Table) for Teaching and Learning Anatomy with the Students
The purpose of this article was to describe and explain our experience with Anatomage table in the process of teaching and learning anatomy to medicine students who are preparing as military physicians. Anatomage combine...
Antimicrobial Peptide Brevinin-2isb, New Drug Candidates Enhance the Innate Immune Response and Cured Caenorhabditis Elegans With Methicillin-Resistant Staphylococcus Aureus (MRSA)
Antimicrobial peptide is supposed to solve the problem of drug resistance by pathogenic bacteria. Brevinin-2ISb is rich in amphibian skin and has been reported to have a wide range antimicrobial activity especially for M...