Modern view on treatment of microsporia of children, taking into account the etiology, pathogenesis and features of clinical course of dermatosis
Journal Title: Український журнал дерматології, венерології, косметології - Year 2018, Vol 0, Issue 4
Abstract
Objective — to analyze publications and summarize literature data on the optimization of the treatment of microsporia of children, taking into account the etiology, pathogenesis and features of the clinical course of dermatosis. Materials and methods. Based on a retrospective analysis of scientific sources and the results of our own research, information on the treatment of microsporia in children is systematized, taking into account the etiology, pathogenesis and features of the clinical course of dermatosis. Results and discussion. Mycotic skin lesions occupy one of the leading places in the structure of dermatovenerological diseases. The high prevalence of fungal infections shows that 20—25 % of the world’s population has skin mycoses, making them one of the most common forms of infection. An important role in the pathogenesis of microsporia is played by various changes in the immune status, the expression of which determine the clinical course of mycosis, its prediction and the choice of rational therapy. Conclusions. At present, complex treatment with the use of systemic antimycotic terbinafine and 2 % sertaconazole nitrate cream is considered effective and safe for microsporia of smooth skin with predominant lesion of vellus hair. Systemic antimycotic grisofulvin combined with the original drug antral proved to be effective and safe in the treatment of microsporia of the scalp in children and adults. Introduction of the probiotic-vitamin-mineral complex Bion 3 Kid in combination with systemic antimycotics griseofulvin, terbinafine and 2 % sertaconazole nitrate cream into the complex of treatment of microsporia contributed to increasing effectiveness of treatment, accelerating clinical and mycological recovery, preventing recurrence of the disease and the occurrence of concurrent cold-related diseases.
Authors and Affiliations
S. I. Lavrushko, V. I. Stepanenko, M. O. Dudchenko, H. P. Pavlenko
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