Modulation of the innate immune responses in the striped snakehead murrel, Channa striata upon experimental infection with live and heat killed Aeromonas hydrophila
Journal Title: Open Veterinary Journal - Year 2017, Vol 7, Issue 2
Abstract
It is well-known that the innate immune mechanisms in fish serve as the first line of defence against wide variety of pathogens. In most of the situations, innate responses get induced and enhanced after the pathogen invasion. It would be interesting to look into the inducibility of various innate immune mechanisms and the level of enhancement after infection with the pathogen. Hence, in the present investigation, modulation of the innate immune responses in the striped snakehead murrel, Channa striata on experimental challenge with either live virulent or heat killed Aeromonas hydrophila at a dose of 1x107 CFU (suspended in 0.2 mL PBS) were measured. Most of the non-specific (both humoral and cellular) immune responses tested were substantially induced or enhanced in both the experimental groups in comparison with the unchallenged control group. Significant increase in the lysozyme, total peroxidase, antiprotease and respiratory burst activities were observed after the pathogen challenge. Thus, most of the innate non-specific immune responses are inducible though they are constitutive of fish immune system exhibiting a basal level of activity even in the absence of pathogen challenge.
Authors and Affiliations
Sekaran Kalaivani Priyadarshini| P.G. and Research Department of Zoology and Biotechnology, Lady Doak College, Madurai-625002, India, Parasuraman Aiya Subramani| Centre for Fish Immunology, School of Life Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), VELS University, Chennai – 600117, India, Rajamani Dinakaran Michael| Centre for Fish Immunology, School of Life Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), VELS University, Chennai – 600117, India
Keywords
Related Articles
- EP ID EP9422
- DOI http://dx.doi.org/10.4314/ovj.v7i2.13
- Views 390
- Downloads 26
Lymph node hemangioma in one-humped camel
Hemangioma is a benign tumor of blood and lymphatic vessels. It is common in skin, mucosa and soft tissues, and its occurrence in lymph nodes is extremely rare. A 10 year-old she-camel was slaughtered at Nyala slaughter...
Determination of cadmium, lead and mercury residual levels in meat of canned light tuna (Katsuwonus pelamis and Thunnus albacares) and fresh little tunny (Euthynnus alletteratus) in Libya
Surveillance for mercury (Hg), lead (Pb) and cadmium (Cd) contamination in tuna products is crucial for consumer food safety. Hg, Pb and Cd contaminants were monitored in a total of 60 specimens of fresh little tunny (E...
First molecular evidence of Toxoplasma gondii in opossums (Didelphis virginiana) from Yucatan, Mexico
Toxoplasma gondii is an obligate intracellular parasite recognized as a causal agent of toxoplasmosis; zoonotic disease endemic in many countries worldwide, including Mexico. Different species of animals participate in...
Expression of various sarcomeric tropomyosin isoforms in equine striated muscles
In order to better understand the training and athletic activity of horses, we must have complete understanding of the isoform diversity of various myofibrillar protein genes like tropomyosin. Tropomyosin (TPM), a coile...
Clinical and ultrasonographic findings of some ocular conditions in sheep and goats
This study was carried out to describe the ultrasonographic findings in relation to the clinical symptoms of some common ocular conditions in sheep and goats. Fifty animals (32 goats and 18 sheep) with different ocular...