Molecular imprinted specific sorbents based on multiwalled carbon nanotube for the detection of progesterone through chromatographic urine analysis
Journal Title: International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS) - Year 2014, Vol 1, Issue 7
Abstract
Molecular imprinting approach was used to synthesize vinyl functionalized carbon nanotube supported progesterone imprinted polymer. The imprinted and non-imprinted polymers were characterized using infrared spectrophotometer, X-ray diffractometer and scanning electron microscopy. The structural superiority of synthesized polymer was reflected by the above measurements. The adsorption behaviour of polymer was evaluated using batch static adsorption experiments by the effect of concentration, temperature, mass, and solvent effect. Meanwhile, it was further demonstrated that the prepared adsorbent has high selectivity towards structurally similar analogues like testosterone and cholesterol. From urine analysis it is very clearly demonstrated the detection of progesterone in urine samples even in low circulating level. The approach we described would provide a new opportunity in the design of polymers with selective recognition properties.
Authors and Affiliations
Anju Augustine, Beena Mathew
Keywords
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