Monozygotic twinning after donor egg intracytoplasmic sperm injection-A case report
Journal Title: Asian Pacific Journal of Reproduction - Year 2018, Vol 7, Issue 5
Abstract
We are reporting a case of monozygotic twinning after donor egg intracytoplasmic sperm injection (ICSI). A 34-year-old lady presented to our centre with primary infertility due to severe endometriosis and low egg reserve. ICSI with donor eggs was planned. A 24 years old voluntary oocyte donor was investigated and stimulated under antagonist protocol. Total 21 eggs and all in metaphase Ⅱ were retrieved. These eggs were injected with the patient’s husband sperms by ICSI. Patient’s endometrial lining was prepared under hormonal replacement therapy protocol. Two expanded blastocysts were transferred on day 5 of progesterone. Beta human chorionic gonadotropin was positive after 10 days. The first antenatal scan at 6 weeks could pick up only two sacs indicating twin conception. Repeat scan at 12 weeks revealed tri-amniotic triplet conception with two foetuses sharing the same placenta (triamniotic pregnancy with monochorionic twins). The patient was counselled about risks associated with triplet conception and was advised of embryo reduction. Two mono chorionic twins were reduced under ultrasonography guidance. Single pregnancy continued till 21 weeks after which the patient miscarried spontaneously. It is difficult to identify the subset of patients at risk for monozygotic twinning; hence, all patients should be counselled about possibility of monozygotic twinning while deciding the number of embryos to be transferred.
Authors and Affiliations
Manjushri Kothekar, Richa Jagtap
Keywords
Related Articles
- EP ID EP407746
- DOI 10.4103/2305-0500.241209
- Views 218
- Downloads 0
Human chorionic gonadotropin in vitro: Effects on rat sperm motility and fertilization outcome
Objective: To investigate the effect of human chorionic gonadotropin (hCG) on the motility of rat sperm and the fertilization rate following in vitro fertilization. Methods: hCG concentrations of 25, 50, 75 and 100 ng/mL...
Monozygotic twinning after donor egg intracytoplasmic sperm injection-A case report
We are reporting a case of monozygotic twinning after donor egg intracytoplasmic sperm injection (ICSI). A 34-year-old lady presented to our centre with primary infertility due to severe endometriosis and low egg reserve...
Effect of different concentration of fish oil in skim milk-egg yolk extenders on post-thawed semen qualities of Kalang swamp buffalo bull
Objective: To explore the effect of fish oil at different concentrations on post-thawed semen of Kalang swamp buffalo. Methods: A total of 4 Kalang swamp buffalo bulls with 3-5 years of age and weighed about 340-360 kg w...
Detection of bacterial biofilm in uterine of repeat breeder dairy cows
Objective: To determine the possibility of presence of bacterial biofilm in the uterus of repeat breeder cows and to evaluate the effect of mucolytic agent in cleanup of uterus from biofilm. Methods: Twenty repeat breede...
Effect of graded doses of acetylsalicylic acid on sperm chromatin integrity and maturity of germinal epithelium in adult male mouse
Objective: To evaluate the effect of graded doses of acetylsalicylic acid (ASA) on sperm chromatin integrity and sex hormones in the adult male mouse. Methods: Forty-nine male adult mice were divided into seven groups. C...