Morphogenesis of colon in human foetuses

Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 9

Abstract

Objective: An attempt is made to histologically and morphologically study the development of colon in foetuses of different gestational ages at Regional Institute of Medical Sciences, Imphal and to compare the findings with those described in the literature. Methods: Fifty foetuses of different gestational ages ranging from eleven weeks to term were fixed for two weeks and dissected. The length, development and position of different parts of colon were charted. Sections were made of the parts and stained with haematoxylin eosin, Masson’s trichrome, plasma stain, Van Giesons stain, Cresyl fast violet stain and were studied for development of various layers of colon. Result:Return of the gut is complete at 11 weeks. Caecum was found to be placed at the iliac crest at 11 weeks, but goes up cranially with relative decrease in size of liver later to descend to lumbar region at 22 weeks. By 24 weeks ascending and descending colon are retroperitonealand transverse colon attains new line of attachment. Sacculations appear at 24 weeks. Sigmoid colon becomes S shaped at 25 weeks. Colon attains its adult position at 31-35 weeks. Histologically lining epithelium was stratified columnar with 2 layered cell thickness with goblet cells at 11 weeks. Mucosal villi like folds are seen at 13 weeks but disappear at 22 weeks. Muscularis mucosa is completely formed at 20 weeks. Taenia coli are seen at 27 weeks.Neurons start appearing in the mesentery by 11 weeks. Conclusion: 50 foetuses from 11 weeks to term were studied morphologically and historically. The foetuses were products of medical termination of pregnancy and still birth.The findings in this study were compared were compared with findings of other authors and were found to be similar.

Authors and Affiliations

HuidromRajshree Devi, Kaini Pfoze, Th. Naranbabu Singh, Y. Ibochouba Singh

Keywords

Related Articles

Estimation of Age by Roentgenologic study of Epiphyseal union at the upper end of Radius in Karnataka.

The present work was undertaken to find out the age of union of epiphysis at the upper end of Radius in males and females. A radiological study was conducted on 100 males and females, in the age group of 13-22 years, res...

Clinical Study of Foreign Body Bronchus

Background: Foreign body in bronchus constitutes one of the acute problems in ent disease, in the absence of proper and clear history, one must not be deceived by the signs and symptoms which simulate many of the pediatr...

Effect of Oral Clonidine Premedication on Perioperative Haemodynamic Response and Postoperative Analgesic Requirement for Patients Undergoing Laparoscopic Cholecystectomy

Objectives: Clonidine is a centrally acting sympatholytic agent with antihypertensive activity. It blunts stress response, provides analgesia, sedation and augments effects of anesthesia. Hence it was hypothesized to be...

Tramadol as an Analgesic to Treat Chronic Pain: A Review

International Association for the Study of Pain (IASP) defines Pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Pain has now...

Non-acceptance of Injectable Contraceptives from Antara Clinic: A Qualitative Study in West Bengal, India

Despite India being the first country in the world to launch a large scale family planning program, the stigma surrounding family planning has been prevailing and contraception has been a bottleneck in the national progr...

Download PDF file
  • EP ID EP395390
  • DOI 10.9790/0853-1709066266.
  • Views 36
  • Downloads 0

How To Cite

HuidromRajshree Devi, Kaini Pfoze, Th. Naranbabu Singh, Y. Ibochouba Singh (2018). Morphogenesis of colon in human foetuses. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 17(9), 62-66. https://europub.co.uk/articles/-A-395390