Morphological changes in the blood of sheep vaccinated against infective agalactia of sheep and goats
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2019, Vol 35, Issue
Abstract
Introduction. Improvement of the existing and development of new means of specific prevention from infectious diseases is important task of the veterinary science. The success in prevention of infectious agalactia of sheep and goats and its elimination depends mostly on the vaccine quality. The goal of the work. To determine the morphological changes in the blood of sheep vaccinated with an inactivated vaccine against infectious agalactia of sheep and goats. Materials and methods. According to the principle of analogues, two groups of sheep (n = 15) were formed with the same conditions of feeding, care and keeping. Control of the vaccine efficacy was performed according to the morphological indicators of blood before vaccination, on the 14th, 21st and 30th days after vaccination, with revaccination on the 60th day. Results of research and discussion. Already on the 14th day, an inactivated vaccine against infectious agalactia of sheep and goats in the experimental group of animals led to an increase in hemoglobin by 6.3% (p<0.05) compared to control, and by 21st day this indicator increased by 8.4%. The number of erythrocytes increased by 22.5% and 22.6%, respectively, and by 18.3% after revaccination. The stimulating effect of inactivated vaccine on myeloid elements of the blood has been established, as the total number of leukocytes had a positive tendency to increase by 19.8%. Synthesis of heparin and histamine is the main function of basophils in the leukogram. The greatest increase in basophils by 40% was recorded on the 30th day after vaccination and by 60% after revaccination. Eosinophil growth by 47.6% and 79% was also reported on the 30th and 60th days respectively. The number of lymphocytes after vaccination increased by 5.8%, and after revaccination - by 11.2%. Thus, a positive correlation of leukocyte content and an absolute lymphocyte count in the experimental group of animals indicates the activation of cellular and humoral immunity. Conclusions and prospects for further research. The increase in the of hemoglobin and erythrocytes level and the absolute lymphocytes count in the peripheral blood of sheep vaccinated with an inactivated vaccine indicated activation of the animal's immune cellular status.
Authors and Affiliations
M. V. Bogach, B. T. Stegniy, D. M. Bogach
Keywords
Related Articles
- EP ID EP659973
- DOI 10.31073/vet_biotech35-01
- Views 111
- Downloads 0
Distribution of animal and poultry salmonellosis in Ukraine in 2015–2018
Introduction. Salmonellosis is a zoonotic infection caused by bacteria of the genus Salmonella. It is one of the most common foodborne diseases. The number of salmonellosis cases continues to be significant in all countr...
Study of biosyntesis of fusarium Moniliforme sheldon that able to produce fumonisins
Introduction. Fumonisins are a group of mycotoxins produced by Fusarium verticilliodes, Fusarium proliferatum and Fusarium moniliforme. These mycotoxins are mainly contaminate corn, thus they are able to accumulate in a...
Determination of stability of utero-tonic drug «Uteroedev»
Introduction. A mandatory condition for the registration of a new drug «Uterodev», which is intended to stimulate reproductive activity, in the treatment of gynecological pathologies and improvement fertilization of anim...
Comparative of analysis morphological characteristics, tinctorial and biochemical properties of pasteurella museumstrains and field isolates
Introduction. The comparative study of morphological, tinctorial, culture and biochemical properties and affiliation with serological groups of the Pasteurella field isolates and P. multocida and P. haemolytica museum st...
Quality and safety of raw cow’s milk in private farms
Introduction. Increased microbial contamination of raw milk is the result of non-compliance with the sanitation requirements of its obtaining, primary processing, cooling, storage and transportation. Analysis of the raw...