MUCOADHESIVE DRUG DELIVERY SYSTEM: A REVIEW
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 12
Abstract
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity. In this regard, this review covers the areas of mechanisms and theories of mucoadhesion, mucoadhesive polymers and also various mucoadhesive dosage forms.
Authors and Affiliations
Rajesh Asija*| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India, Jitendra Kumar Kumawat| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India, Deepak Sharma| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India
Formulation & evaluation of voriconazole ointment for topical delivery
The studies were conducted with an object to develop a desired ointment for treatment of fungal infection like eczema itching, purities’. Main objective of this study is to formulate the ointment with different ointment...
A review on antihyperlipidemic activity of various herbal plants and various experimental animal models
Hyperlipidemia is a disorder of lipid metabolism which is major risk of coronary heart disease. Now day’s synthetic drugs have been associated with number of side effects but herbal medicines have lipid lowering and anti...
Analgesic effect of methanolic extract of Vetiveria zizanoides in wistar rats
Introduction: Vetiveria zizanoides is used as a traditional medicine for a number of conditions, but there is lack of scientific data regarding its analgesic action.Aim: to study the analgesic action of methanolic extrac...
PHOSPHOLIPASE A2 IN AIRWAY DISEASES: TARGET FOR DRUG DISCOVERY
Importance of the Field: Inflammatory airway diseases are on the rise world over. There is need for orally active, safe and efficacious antiinflammatory agent. Existing therapeutic options are plagued by poor efficacy an...
COMPREHENSIVE REVIEW ON PULSATILE DRUG DELIVERY SYSTEM
Oral controlled drug delivery systems represent the most popular form of controlled drug delivery systems for the obvious advantages of oral route of drug administration. However, there are certain conditions for which s...