MUCOADHESIVE DRUG DELIVERY SYSTEM: A REVIEW
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 12
Abstract
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity. In this regard, this review covers the areas of mechanisms and theories of mucoadhesion, mucoadhesive polymers and also various mucoadhesive dosage forms.
Authors and Affiliations
Rajesh Asija*| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India, Jitendra Kumar Kumawat| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India, Deepak Sharma| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India
Keywords
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