Mucoepidermoid Carcinoma of Salivary Gland: Limitations and Pitfalls on FNA
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 5
Abstract
Mucoepidermoid Carcinoma (MEC) is the most common malignant neoplasm of salivary gland origin. However, its morphologic heterogeneity poses difficulty in interpretation. In the present series we discuss the morphologic features of MEC, limitations and pitfalls in its diagnosis on Fine Needle Aspiration Cytology (FNAC). Fourteen cases of suspected MEC were evaluated cytologically followed by histopathological examination for confirmation. A definite cytological diagnosis was rendered in nine cases; three of the remaining five were underdiagnosed as abscess, pleomorphic adenoma and mucus cyst. Of the remaining two cases, one case each of sebaceous carcinoma and sialadenitis was mislabeled as MEC on cytology. A satisfactory aspirate composed of intermediate cells, mucin secreting cells and squamous cells in a mucinous background may not be obtained in all cases of low grade MEC. High grade MEC can be classified as squamous cell carcinoma. Hence, awareness of confounding factors with clinicopathologic correlation and judicious use of frozen section can help in minimizing errors.
Authors and Affiliations
Geetha Vasudevan, Arijit Bishnu, Brij Mohan Kumar Singh, Varun Kumar Singh
Keywords
Related Articles
- EP ID EP342134
- DOI 10.7860/JCDR/2017/25341.9941
- Views 79
- Downloads 0
Bite of a Mite: A Case of Human Otoacariasis caused by Cosmoglyphus Species (Acari: Acaridae)
Otoacariasis or parasitic otitis, is the infestation of the ear with ticks/mites and is a common condition in the livestock and domestic animals. Although, less common, cases of human otoacariasis caused by mites can be...
Histogenesis of Muscularis Mucosa and Muscularis Externa of Stomach: A Human Foetal Study
Introduction: The histological and developmental knowledge of musculature of stomach wall is vital for the assessment and management of various associated congenital abnormalities like hypertrophy of pyloric musculature...
Reconstruction of Maxilla with Titanium Mesh and Fascia Lata - A Case Report
Maxillary defect reconstruction has been a grave challenge which unfortunately has stopped many ENT surgeons from attempting maxillectomy due to the fear of reconstruction. With our technique of reconstructing the maxill...
Ultrasound Guided Percutaneous Injection of Thrombin: Effective Technique for Treatment of Iatrogenic Femoral Pseudoaneurysms
Introduction: Arterial pseudoaneurysms are well known iatrogenic complication of percutaneous angiographic or interventional vascular procedures. In the past, the definitive treatment option was open surgical repair whic...
Accuracy of Sonographic Modules in the Estimation of Birth Weight: An Analytical Study of Antenatal Women in Enugu, Nigeria
ABSTRACT Introduction: Antenatal sonographic estimation of foetal weight is a common practice. The use of these estimates to predict actual birth weight is crucial for appropriate management of certain pregnancy conditio...