Mucoepidermoid Carcinoma of Salivary Gland: Limitations and Pitfalls on FNA
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 5
Abstract
Mucoepidermoid Carcinoma (MEC) is the most common malignant neoplasm of salivary gland origin. However, its morphologic heterogeneity poses difficulty in interpretation. In the present series we discuss the morphologic features of MEC, limitations and pitfalls in its diagnosis on Fine Needle Aspiration Cytology (FNAC). Fourteen cases of suspected MEC were evaluated cytologically followed by histopathological examination for confirmation. A definite cytological diagnosis was rendered in nine cases; three of the remaining five were underdiagnosed as abscess, pleomorphic adenoma and mucus cyst. Of the remaining two cases, one case each of sebaceous carcinoma and sialadenitis was mislabeled as MEC on cytology. A satisfactory aspirate composed of intermediate cells, mucin secreting cells and squamous cells in a mucinous background may not be obtained in all cases of low grade MEC. High grade MEC can be classified as squamous cell carcinoma. Hence, awareness of confounding factors with clinicopathologic correlation and judicious use of frozen section can help in minimizing errors.
Authors and Affiliations
Geetha Vasudevan, Arijit Bishnu, Brij Mohan Kumar Singh, Varun Kumar Singh
Keywords
Related Articles
- EP ID EP342134
- DOI 10.7860/JCDR/2017/25341.9941
- Views 84
- Downloads 0
Sclerosing Mediastinitis Presenting as Complete Heart Block
Sclerosing Mediastinitis (SM) is a rare condition which is characterized by the presence of dense fibrosis which infiltrates and encroaches upon various structures in the mediastinal cavity. Depending on the extent and t...
Comparative Study of 3% Hypertonic Saline Nebulisation Versus 0.9% Normal Saline Nebulisation for Treating Acute Bronchiolitis
ABSTRACT Introduction: Bronchiolitis is commonly noticed condition in children, especially in infants and characterised by inflammation of bronchioles. Inspite of this common occurrence the evidence for the treatment opt...
Retained Foetal Bones with Recurrent Vaginal Discharge: A Case Report
Termination of pregnancy or abortion is rarely known to result in retained foetal bones. The presentation of a patient with retained foetal bones may be in the form of secondary infertility, chronic pelvic pain, dysmenor...
Anti-hypertriglyceridemic Activity of Cornus Mas in Diabetic Rats
ABSTRACT Introduction: Hypertriglyceridemia is among the multiple metabolic derangements seen in diabetes mellitus. Cornelian cherry (Cornus mas L.), belongs to the family Cornacea and has been shown to be helpful in tre...
Healthcare Associated Infection in Paediatric Intensive Care Unit-A Tertiary Care Hospital Experience
ABSTRACT Introduction: Healthcare Associated Infections (HAI) are those that are acquired in a health care setting or one that is acquired in the hospital environment by a patient who had been admitted to the hospital f...